Systemic therapy for early-stage breast cancer: learning from the past to build the future

Nature Reviews Clinical Oncology, Published online: 17 October 2022; doi:10.1038/s41571-022-00687-1Systemic therapies for early-stage disease have been tested in clinical trials for decades. The authors of this Review provide an overview of the evolution of (neo)adjuvant trials from the pre-genomic to the post-genomic era, focusing on design, end points and biomarkers that, together, could enable the delivery of more personalized treatment.
Source: Nature Reviews Clinical Oncology - Category: Cancer & Oncology Authors: Source Type: research