Effect of a toothpaste containing S-PRG filler on the remineralization of artificial carious enamel lesions in situ

This study evaluated the remineralizing effect of a toothpaste containing surface pre-reacted glass-ionomer (S-PRG) filler on demineralized enamel in situ. For this, 180 bovine enamel samples were demineralized by using a microcosm biofilm model for 3 days. Thereafter, the samples were randomly signed to 15 healthy volunteers and to 3 cross-over in situ phases corresponding to the following treatments: 1) toothpaste containing 1500 ppm F as NaMFP (positive control, Colgate ® Cavity Protection), 2) toothpaste containing 5% S-PRG filler (Shofu®), and 3) placebo toothpaste (negative control prepared by Shofu®). Four demineralized enamel blocks were fixed into each palatal appliance per phase. The volunteers wore the appliances for 5 days and were trained to brush thei r teeth 2 times for 2 minute a day, while one drop of the toothpaste’s slurry (1:3) was dripped on each sample for the same period. The surface hardness and TMR analyses were done and analyzed by ANOVA/Tukey and t test (p

Source: Caries Research - October 10, 2022 Category: Dentistry Source Type: research