Wound Healing After Fractional Skin Harvesting

BACKGROUND

Autologous fractional full-thickness skin grafting is a method of harvesting full-thickness skin with reduced donor site morbidity compared with conventional skin grafting.

OBJECTIVE

To demonstrate that full-thickness skin microbiopsies can be harvested with minimal scarring or complications.

MATERIALS AND METHODS

In a nonrandomized, self-controlled, pilot trial, subjects (n = 8) underwent tissue harvesting of full-thickness skin columns of 200, 400, 500, 600, 800 μm, 1, and 2 mm diameters. The extent of scarring was measured by using the Patient and Observer Scar Assessment Scale and blinded evaluation of photographs at 6 weeks postprocedure. Pain visual analog scale (VAS) and side effects were recorded.

RESULTS

When present, scars were first observed after 2 to 4 weeks, much more often for wounds>400 μm (p

Source: Dermatologic Surgery - October 1, 2022 Category: Dermatology Tags: Original Article Source Type: research