Precision Implementation: An Approach to Mechanism Testing in Implementation Research

We describe further advancement of experimental therapeutics along the translational spectrum and describe how it is ideally suited to inform precision experimental tests of implementation strategy mechanisms, which we termprecision implementation. Such an approach to mechanism testing will allow for identification of causal dose-response relationships between implementation strategies, presumed mechanisms, and implementation outcomes. We discuss the tension between the scientific rigor required to conduct mechanism-focused research using experimental therapeutics and the “real world” conditions in which implementation research takes place. We provide a series of example studies that show “beginning to end” application of this framework in research focused on provider implementation of an evidence-based intervention in routine clinical care settings.

Source: Administration and Policy in Mental Health and Mental Health Services Research - September 27, 2022 Category: Psychiatry Source Type: research