Mechanisms of the intestinal and urinary microbiome in kidney stone disease

Nature Reviews Urology, Published online: 20 September 2022; doi:10.1038/s41585-022-00647-5Evidence has suggested that the intestinal microbiome might have a role in maintaining oxalate homeostasis and kidney stone disease and that the urinary microbiome might also influence the induction of crystal formation and stone growth directly in the kidney. In this Review, the authors discuss the mechanisms by which these microbial populations contribute to stone disease and how they might be therapeutically targeted.
Source: Nature Reviews Urology - Category: Urology & Nephrology Authors: Source Type: research