Emerging concepts of type I interferons in SLE pathogenesis and therapy

Nature Reviews Rheumatology, Published online: 12 September 2022; doi:10.1038/s41584-022-00826-zIn this Review, Psarras, Wittmann and Vital discuss evidence of the production of type I interferons by cells and tissues other than haematopoietic cells. These interferons can have local effects, and their roles in the pathogenesis of systemic lupus erythematosus suggest the value of interferon-blocking therapies for treatment of this condition.

Source: Nature Reviews Rheumatology - September 12, 2022 Category: Rheumatology Authors: Antonios Psarras Miriam Wittmann Edward M. Vital Source Type: research