THZ1 targeting CDK7 suppresses c-KIT transcriptional activity in gastrointestinal stromal tumours

Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the gastrointestinal tract and are characterized by activating mutations of c-KIT or PDGFRa receptor tyrosine kinases (RTKs)....

https://biosignaling.biomedcentral.com/articles/10.1186/s12964-022-00928-x

Source: Cell Communication and Signaling - September 8, 2022 Category: Molecular Biology Authors: Jianyi Sun, Qiang Zhang, Xiangfei Sun, Anwei Xue, Xiaodong Gao and Kuntang Shen Tags: Research Source Type: research

More News: Gastroenterology | Gastrointestinal Stromal Tumor (GIST) | Gastrointestinal Stromal Tumour (GIST) | Molecular Biology