New evidence for the ‘cusp theory’ to explain HLA associations in SLE

Nature Reviews Rheumatology, Published online: 06 September 2022; doi:10.1038/s41584-022-00835-yNew findings support the existence of an antigen presentation-independent mechanism known as the ‘cusp theory’ and the involvement of a newly discovered ‘lupus epitope’ in systemic lupus erythematosus susceptibility.

Source: Nature Reviews Rheumatology - September 6, 2022 Category: Rheumatology Authors: Jessica McHugh Source Type: research