Novel JAK3-specific inhibitor safe and effective in mouse RA model

Nature Reviews Rheumatology, Published online: 07 September 2022; doi:10.1038/s41584-022-00839-8The newly developed Z583 is a potent and highly specific inhibitor of JAK3, with a favourable in vitro and in vivo safety profile and effectiveness in treatment of collagen-induced arthritis in mice.

Source: Nature Reviews Rheumatology - September 7, 2022 Category: Rheumatology Authors: Robert Phillips Source Type: research