Biallelic variants in ZFP36L2 cause female infertility characterised by recurrent preimplantation embryo arrest

Conclusion
These findings emphasise the relevance of the relationship between maternal mRNA decay and human preimplantation embryo development and highlight a novel gene potentially responsible for RPEA, which may facilitate genetic diagnoses.

Source: Journal of Medical Genetics - August 19, 2022 Category: Genetics & Stem Cells Authors: Zheng, W., Sha, Q.-Q., Hu, H., Meng, F., Zhou, Q., Chen, X., Zhang, S., Gu, Y., Yan, X., Zhao, L., Zong, Y., Hu, L., Gong, F., Lu, G., Fan, H.-Y., Lin, G. Tags: Genotype-phenotype correlations Source Type: research