A polygenic score predicts CKD across ancestries

Nature Reviews Nephrology, Published online: 11 August 2022; doi:10.1038/s41581-022-00622-8Chronic kidney disease (CKD) is often well advanced before it is detected. Although polygenic scores may enable the early stratification of patients at risk of CKD, the transferability of polygenic scores for the prediction of CKD to populations of non-European ancestry was limited. A new cross-ancestry polygenic score for CKD overcomes these issues, demonstrating good performance across ancestries.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research