VCAM-1-binding peptide targeted cationic liposomes containing NLRP3 siRNA to modulate LDL transcytosis as a novel therapy for experimental atherosclerosis

Activation of NLRP3 inflammasome accelerates the formation of atherosclerotic plaques. Here, we evaluated the effects of inflammation on the expression of the NLRP3 inflammasome in endothelial cells (ECs).

Source: Metabolism - Clinical and Experimental - July 30, 2022 Category: Biomedical Science Authors: Xiong Jia, Xiangli Bai, Xiaoyan Yang, Ling Wang, Yajing Lu, Lin Zhu, Ying Zhao, Wenzhuo Cheng, Meng Shu, Qiyong Mei, Si Jin Source Type: research