Clinical presentation and serological diagnosis of syphilis reinfection in men living with HIV: a retrospective cohort study

Conclusions Our data highlight the paramount importance of regularly screening patients at risk as syphilis reinfections in men living with HIV are more likely to be latent infections, that is, without symptoms. As non-treponemal tests might be biologically false-positive (up to a titre of 1:8) due to various conditions, a ≥fourfold increase of the TPPA might be considered as optional criterion for the diagnosis of syphilis reinfections. This could be especially valuable for diagnosing reinfected latent stage patients.
Source: Sexually Transmitted Infections - Category: Sexual Medicine Authors: Tags: Clinical Source Type: research