Diversity in EWAS: current state, challenges, and solutions

AbstractHere, we report a lack of diversity in epigenome-wide association studies (EWAS) and DNA methylation (DNAm) data, discuss current challenges, and propose solutions for EWAS and DNAm research in diverse populations. The strategies  we propose include fostering community involvement, new data generation, and cost-effective approaches such as locus-specific analysis and ancestry variable region analysis.

Source: Genome Medicine - July 6, 2022 Category: Genetics & Stem Cells Source Type: research