Prolactin immunoassay: does the high-dose hook effect still exist?

ConclusionThe high-dose hook effect still exists in a very small minority of prolactin assays. The evolution of assay methods may lead to new assays that remain sensitive to this effect in the future. We therefore advise that the hook effect should still be mentioned in prolactin assay recommendations.
Source: Pituitary - Category: Endocrinology Source Type: research