Hypoxia promotes extravillous trophoblast cell invasion through the hypoxia-inducible factor urokinase-type plasminogen activator receptor pathway.

Conclusions:
The low oxygen-regulated early events of EVT invasion may be mediated by the HIF-1α-uPAR pathway.

Source: Gynecologic and Obstetric Investigation - July 4, 2022 Category: OBGYN Source Type: research