The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes

HIV eradication efforts have been unsuccessful partly due to virus persistence in immune sanctuary sites such as germinal centres within lymph node (LN) tissues. Recent evidence suggests that LNs harbour a nov...

Source: BMC Immunology - July 1, 2022 Category: Allergy & Immunology Authors: Bongiwe Mahlobo, Faatima Laher, Werner Smidt, Funsho Ogunshola, Trevor Khaba, Thandeka Nkosi, Anele Mbatha, Thandekile Ngubane, Krista Dong, Ismail Jajbhay, Johan Pansegrouw and Zaza M. Ndhlovu Tags: Research Source Type: research