The effect of HIF on metabolism and immunity

Nature Reviews Nephrology, Published online: 20 June 2022; doi:10.1038/s41581-022-00587-8Hypoxia-dependent changes in cellular metabolism have important implications for the effective functioning of multiple immune cell subtypes. This Review describes the inputs that shape the hypoxic response in individual cell types and contexts, and the implications of this response for cellular metabolism and associated alterations in immune cell function.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research