Data analytics improves the diagnostic accuracy of serum free light chain results for detecting monoclonal gammopathy
CONCLUSIONS: Our analysis indicated that revision of Freelite SFLC reference intervals improves assay interpretation and should prompt reconsideration of Freelite reference intervals worldwide.PMID:37936261 | DOI:10.1093/ajcp/aqad137 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Rebecca S Treger Patrick C Mathias Andrew J Cowan Damian Green Kathleen Hutchinson Andrew Bryan Anu Chaudhary Susan L Fink Mark H Wener Chihiro Morishima Source Type: research

Monkeypox virus cytologic findings
Am J Clin Pathol. 2023 Nov 4:aqad133. doi: 10.1093/ajcp/aqad133. Online ahead of print.NO ABSTRACTPMID:37936264 | DOI:10.1093/ajcp/aqad133 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Amnuay Kleebayoon Viroj Wiwanitkit Md Source Type: research

Reply to "Monkeypox virus cytologic findings"
Am J Clin Pathol. 2023 Nov 4:aqad134. doi: 10.1093/ajcp/aqad134. Online ahead of print.NO ABSTRACTPMID:37936266 | DOI:10.1093/ajcp/aqad134 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Jeannette Guarner Kartik Viswanathan Daniel J Lubin Source Type: research

The American Society for Clinical Pathology 2022 Vacancy Survey of medical laboratories in the United States
CONCLUSIONS: Current Vacancy Survey data show continued increases in the numbers of laboratory vacancies and retirements as well as changes in certification requirements, with trends amplified during the pandemic continuing into the present. Qualitative analysis results showed that there is an urgent need to focus not only on recruitment but-equally important-on retention of laboratory professionals.PMID:37936416 | DOI:10.1093/ajcp/aqad149 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Edna Garcia Iman Kundu Melissa Kelly Ryan Soles Source Type: research

Applicability of the cobas 6800 System for Epstein-Barr viral load quantitation using whole-blood specimens
CONCLUSIONS: A significant discrepancy was observed in the results obtained from the 2 assays because of the different specimens used. We observed, however, that diluting whole blood before conducting the cobas EBV test effectively resolved polymerase chain reaction inhibition and viscosity issues, leading to an acceptable correlation with the results from the artus EBV RG PCR Kit conducted using whole blood.PMID:37936258 | DOI:10.1093/ajcp/aqad146 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Junhyup Song Sinyoung Kim Eunmin Kwak Younhee Park Source Type: research

Performance evaluation of heparin-induced platelet aggregation vs serotonin release assay
CONCLUSIONS: Although the HIPA has a lower sensitivity than the SRA, the new standardized interpretation guide improved its sensitivity and NPV in 2022. Future improvements are needed to use the HIPA as a stand-alone confirmatory test with the goal to shorten hospital length of stay and expedite proper anticoagulation management.PMID:37936260 | DOI:10.1093/ajcp/aqad117 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Mohammad Barouqa Milad Matta Morayma Reyes-Gil Source Type: research

Data analytics improves the diagnostic accuracy of serum free light chain results for detecting monoclonal gammopathy
CONCLUSIONS: Our analysis indicated that revision of Freelite SFLC reference intervals improves assay interpretation and should prompt reconsideration of Freelite reference intervals worldwide.PMID:37936261 | DOI:10.1093/ajcp/aqad137 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Rebecca S Treger Patrick C Mathias Andrew J Cowan Damian Green Kathleen Hutchinson Andrew Bryan Anu Chaudhary Susan L Fink Mark H Wener Chihiro Morishima Source Type: research

Monkeypox virus cytologic findings
Am J Clin Pathol. 2023 Nov 4:aqad133. doi: 10.1093/ajcp/aqad133. Online ahead of print.NO ABSTRACTPMID:37936264 | DOI:10.1093/ajcp/aqad133 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Amnuay Kleebayoon Viroj Wiwanitkit Md Source Type: research

Reply to "Monkeypox virus cytologic findings"
Am J Clin Pathol. 2023 Nov 4:aqad134. doi: 10.1093/ajcp/aqad134. Online ahead of print.NO ABSTRACTPMID:37936266 | DOI:10.1093/ajcp/aqad134 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Jeannette Guarner Kartik Viswanathan Daniel J Lubin Source Type: research

The American Society for Clinical Pathology 2022 Vacancy Survey of medical laboratories in the United States
CONCLUSIONS: Current Vacancy Survey data show continued increases in the numbers of laboratory vacancies and retirements as well as changes in certification requirements, with trends amplified during the pandemic continuing into the present. Qualitative analysis results showed that there is an urgent need to focus not only on recruitment but-equally important-on retention of laboratory professionals.PMID:37936416 | DOI:10.1093/ajcp/aqad149 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 8, 2023 Category: Pathology Authors: Edna Garcia Iman Kundu Melissa Kelly Ryan Soles Source Type: research

The importance of fetal autopsy: An institutional review and development of best practices for reporting size and estimating gestational age at demise
CONCLUSIONS: "Best practice" suggestions for sizing and dating fetuses/neonates in the postmortem period have been developed to aid in delivering clear, consistent reports. Because fetal and neonatal autopsy is an invaluable tool for understanding the factors that contribute to stillbirth, it is important to use appropriate sizing and dating methods and consistent language to deliver proper patient education and clinical guidance.PMID:37921079 | DOI:10.1093/ajcp/aqad147 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 3, 2023 Category: Pathology Authors: Elizabeth S Doughty Kimi N Verilhac Sterling McLaren Miriam D Post Source Type: research

Immune microenvironment of intimal sarcomas: Adaptive immune resistance with potential therapeutic implications
CONCLUSIONS: These data show that intimal sarcomas have an active tumor microenvironment with an adaptive pattern of PD-L1 expression. Our results suggest that immunotherapy may be an effective treatment option.PMID:37921094 | DOI:10.1093/ajcp/aqad142 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 3, 2023 Category: Pathology Authors: Jacqueline E Birkness-Gartman Dwayne L Thomas Logan L Engle Lysandra Voltaggio Elizabeth D Thompson Source Type: research

The importance of fetal autopsy: An institutional review and development of best practices for reporting size and estimating gestational age at demise
CONCLUSIONS: "Best practice" suggestions for sizing and dating fetuses/neonates in the postmortem period have been developed to aid in delivering clear, consistent reports. Because fetal and neonatal autopsy is an invaluable tool for understanding the factors that contribute to stillbirth, it is important to use appropriate sizing and dating methods and consistent language to deliver proper patient education and clinical guidance.PMID:37921079 | DOI:10.1093/ajcp/aqad147 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 3, 2023 Category: Pathology Authors: Elizabeth S Doughty Kimi N Verilhac Sterling McLaren Miriam D Post Source Type: research

Immune microenvironment of intimal sarcomas: Adaptive immune resistance with potential therapeutic implications
CONCLUSIONS: These data show that intimal sarcomas have an active tumor microenvironment with an adaptive pattern of PD-L1 expression. Our results suggest that immunotherapy may be an effective treatment option.PMID:37921094 | DOI:10.1093/ajcp/aqad142 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 3, 2023 Category: Pathology Authors: Jacqueline E Birkness-Gartman Dwayne L Thomas Logan L Engle Lysandra Voltaggio Elizabeth D Thompson Source Type: research

The importance of fetal autopsy: An institutional review and development of best practices for reporting size and estimating gestational age at demise
CONCLUSIONS: "Best practice" suggestions for sizing and dating fetuses/neonates in the postmortem period have been developed to aid in delivering clear, consistent reports. Because fetal and neonatal autopsy is an invaluable tool for understanding the factors that contribute to stillbirth, it is important to use appropriate sizing and dating methods and consistent language to deliver proper patient education and clinical guidance.PMID:37921079 | DOI:10.1093/ajcp/aqad147 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 3, 2023 Category: Pathology Authors: Elizabeth S Doughty Kimi N Verilhac Sterling McLaren Miriam D Post Source Type: research