American Journal of Clinical Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The utility of the dilute prothrombin time in the interpretation of antiphospholipid syndrome testing
CONCLUSIONS: Dilute prothrombin time lupus anticoagulant assay is rarely the sole laboratory functional evidence for APS, but when combined with the DRVVT, the DPT can serve as an effective screen for common anticoagulant interference.PMID:38741421 | DOI:10.1093/ajcp/aqae044 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 14, 2024 Category: Pathology Authors: Noah A Mehr Tanner E Storozuk Krzysztof L Mikrut Geoffrey D Wool Source Type: research

Lost, mislabeled, and mishandled surgical and clinical pathology specimens: A systematic review of published literature
CONCLUSIONS: The review highlights the limited research on the topic, with an average of 2 articles per year discussing lost, mislabeled, or mishandled specimens. Intervention studies addressed The Joint Commission's patient safety goals for laboratory practice. More research is needed about error incidents and reporting in non-Western countries to gain a more global perspective on the topic.PMID:38738289 | DOI:10.1093/ajcp/aqae055 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 13, 2024 Category: Pathology Authors: Heather J Carmack Braidyn S Lazenby Kylie J Wilson Jamie N Bakkum-Gamez Leslie Carranza Source Type: research

Tennessee hospital noncompliance with price transparency legislation for 8 common laboratory tests
CONCLUSIONS: Our study showed high levels of noncompliance with price transparency laws, inconsistent and inaccessible pricing, and continued challenges facing patients in Tennessee.PMID:38733607 | DOI:10.1093/ajcp/aqae057 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 11, 2024 Category: Pathology Authors: Stephanie A Hart Ayesha Khan Garrett S Booth Joesph R Wiencek Source Type: research

Harmonizing tumor mutational burden analysis: Insights from a multicenter study using in silico reference data sets in clinical whole-exome sequencing (WES)
CONCLUSIONS: This study highlights real-world challenges in WES-based TMB analysis that need to be improved and optimized. This research will aid in the selection of more reasonable analytical procedures to minimize potential methodologic biases in estimating TMB in clinical exome sequencing tests. Harmonizing TMB estimation in clinical testing conditions is crucial for accurately evaluating patients' response to immunotherapy.PMID:38733635 | DOI:10.1093/ajcp/aqae056 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 11, 2024 Category: Pathology Authors: Lijia Yu Yuanfeng Zhang Duo Wang Lin Li Rui Zhang Jinming Li Source Type: research

Artificial intelligence-aided steatosis assessment in donor livers according to the Banff consensus recommendations
CONCLUSIONS: The 3-step approach proposed by the Banff Working Group on Liver Allograft Pathology may be followed when evaluating steatosis in donor livers. The AI model can provide a rapid and objective assessment of liver steatosis.PMID:38716796 | DOI:10.1093/ajcp/aqae053 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 8, 2024 Category: Pathology Authors: Jingjing Jiao Haiming Tang Nanfei Sun Xuchen Zhang Source Type: research

Establishing hemolysis, icterus, and lipemia interference limits for body fluid chemistry analytes measured on the Roche cobas instrument
CONCLUSIONS: Interference thresholds in body fluids were lower than blood for 6 analytes. Diluting interferences that surpass these limits does not produce reliable results that are comparable to the baseline results before spiking in the interferent.PMID:38709595 | DOI:10.1093/ajcp/aqae040 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 6, 2024 Category: Pathology Authors: Darci R Block Michael A Lasho Leslie J Donato Jeffrey W Meeusen Source Type: research

Dilute Russell viper venom time interpretation: Influence of lot changes and normalization
Am J Clin Pathol. 2024 May 4:aqae054. doi: 10.1093/ajcp/aqae054. Online ahead of print.NO ABSTRACTPMID:38703058 | DOI:10.1093/ajcp/aqae054 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - May 4, 2024 Category: Pathology Authors: Geoffrey D Wool Source Type: research