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Low‐level laser therapy (810 nm) protects primary cortical neurons against excitotoxicity in vitro
Abstract Excitotoxicity describes a pathogenic process whereby death of neurons releases large amounts of the excitatory neurotransmitter glutamate, which then proceeds to activate a set of glutamatergic receptors on neighboring neurons (glutamate, N‐methyl‐D‐aspartate (NMDA), and kainate), opening ion channels leading to an influx of calcium ions producing mitochondrial dysfunction and cell death. Excitotoxicity contributes to brain damage after stroke, traumatic brain injury, and neurodegenerative diseases, and is also involved in spinal cord injury. We tested whether low level laser (light) therapy (LLLT) at 810 n...
Source: Journal of Biophotonics - October 1, 2013 Category: Physics Authors: Ying‐Ying Huang, Kazuya Nagata, Clark E Tedford, Michael R. Hamblin* Tags: Full Article Source Type: research