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Outcomes of Thrombolytic Treatment for Acute Ischemic Stroke in Dialysis Dependant Patients in the United States (S02.003)
CONCLUSIONS: The three fold higher odds of in-hospital mortality associated with administration of IV thrombolytics in dialysis dependant patients who present with acute ischemic stroke warrants a careful assessment of risk benefit ratio in this population.Disclosure: Dr. Adil has nothing to disclose. Dr. Adil has nothing to disclose. Dr. Irfan has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. ATACH Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Tariq, N., Adil, M., Irfan, M., Chaudhry, S., Qureshi, A. Tags: S02 Acute Stroke Therapy Source Type: research

Variables affecting Stroke Outcome for TPA received between 3 to 4.5 hours (P2.301)
Conclusions: Age, NIHSS and renal dysfunction were significantly associated with worse outcome in patients who had received t-PA between 3 to 4.5 hours. Our findings were consistent but more robust than previous studies showing poorer outcome with renal dysfunction (Meta-analysis OR1.06 NS). After controlling for age and NIHSS, diabetes or hypertension did not additionally contribute to poor outcome. Prognostic and risk stratification scales are useful as predictors of outcome but do not imply efficacy of t-PA therapy or lack thereof.Disclosure: Dr. Yeo has nothing to disclose. Dr. McCane has nothing to disclose. Dr. Katz ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Yeo, C., McCane, D., Katz, L., Ling, K., Capetillo, A., Bledsoe, D., Chiu, D. Tags: Acute Therapy: IV t-PA Source Type: research

Spinal ischemic stroke following dialysis: clinical and radiologic findings
Spinal cord ischemia (SCI) is a relatively common cause of noncompressive myelopathy.1 SCI frequently involves the thoracic or lumbar cord manifesting as acute painful paraparesis but may also involve the posterior columns and autonomic fibers.2 Most infarcts affect the central parts of the anterior spinal artery supply.2–4 Outcome depends on the initial severity of the neurologic deficits and may be surprisingly benign especially if proprioception remains intact.1,2 Because hypoperfusion may cause SCI,5,6 our goal was to describe SCI as a potential complication of hemodialysis-associated hypoperfusion.
Source: Neurology - February 25, 2013 Category: Neurology Authors: Honig, A., Gomori, J. M., Schneider, R., Makranz, C., Leker, R. R. Tags: All Medical/Systemic disease, All Cerebrovascular disease/Stroke, All Spinal Cord, Spinal cord infarction, Infarction CLINICAL/SCIENTIFIC NOTES Source Type: research

Frequency of and risk factors for poor cognitive performance in hemodialysis patients
Conclusions: There is a high frequency of poor cognitive performance in hemodialysis patients, primarily affecting executive function. Risk factors for worse executive function include vascular risk factors as well as vascular disease. Normal performance on the MMSE does not preclude impaired cognitive function, because individuals with MMSE score ≥24 also have a high frequency of poor cognitive performance.
Source: Neurology - January 28, 2013 Category: Neurology Authors: Sarnak, M. J., Tighiouart, H., Scott, T. M., Lou, K. V., Sorensen, E. P., Giang, L. M., Drew, D. A., Shaffi, K., Strom, J. A., Singh, A. K., Weiner, D. E. Tags: All Cerebrovascular disease/Stroke, Memory, Neuropsychological assessment, Executive function ARTICLE Source Type: research

Lacunar Infarct Presenting Like Axillary Nerve Lesion: A Case Report (P6.250)
Conclusion: Our case was thought like an axillary nerve lession primarily as a result of history and physical examination. But after the tests our diagnosis was an infarct. We can’t find affected only proximal upper extremities like axillary nerve lesion in the literature. We want to point to lacuner infarct that can be presented like peripheral nerve lesion.Disclosure: Dr. Oz has nothing to disclose. Dr. Tasdemir has nothing to disclose. Dr. Akgun has nothing to disclose. Dr. Alay has nothing to disclose. Dr. Cetiz has nothing to disclose. Dr. Odabasi has nothing to disclose. Dr. Demirkaya has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Oz, O., Tasdemir, S., Akgun, H., Alay, S., Cetiz, A., Odabasi, Z., Demirkaya, S. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Subarachnoid Hemorrhage as the Initial Neurologic Manifestation in Thrombotic Thrombocytopenic Purpura (P6.014)
Conclusion: Upon review of the literature, ischemic infarction and intracerebral hemorrhage are uncommon complications of TTP. Our case demonstrates a unique case of subarachnoid hemorrhage as the initial neurological manifestation of TTP.Disclosure: Dr. Wei has nothing to disclose. Dr. Ramesh has nothing to disclose. Dr. Farmakidis has nothing to disclose. Dr. Nalleballe has nothing to disclose. Dr. JADEJA has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Wei, J., Ramesh, A., Farmakidis, C., Nalleballe, K., Jadeja, N. Tags: Cerebrovascular Disease and Interventional Neurology II ePosters Source Type: research

Elevated ventricular CSF lactate within the first week after aneurysmal subarachnoid hemorrhage is associated with poor outcome (P5.068)
Conclusions:Elevated CSF lactate drawn within the first week of hospitalization following aSAH correlates with outcome. Larger prospective studies are needed to test the validity of this data for predicting outcome and for understanding the pathophysiologic mechanisms.Study Supported by: No funding was received for this study.Disclosure: Dr. Renfrow has nothing to disclose. Dr. Wilson has nothing to disclose. Dr. Arnel has nothing to disclose. Dr. Wolfe has nothing to disclose. Dr. Datar has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Renfrow, J., Wilson, T., Arnel, M., Wolfe, S., Datar, S. Tags: Neurocritical Care: Subarachnoid Hemorrhage Source Type: research