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Cardiovascular effects of dexmedetomidine, with or without MK ‐467, following intravenous administration in cats
Conclusion and clinical relevanceFollowing IV co‐administration, MK‐467 effectively attenuated dexmedetomidine‐induced cardiovascular effects in cats. The drug combination resulted in transient reduction in arterial blood pressure, without causing hypotension.
Source: Veterinary Anaesthesia and Analgesia - July 4, 2016 Category: Veterinary Research Authors: Bruno H Pypendop, Juhana Honkavaara, Jan E Ilkiw Tags: Research Paper Source Type: research

Cardiovascular effects of dexmedetomidine, with or without MK‐467, following intravenous administration in cats
Conclusion and clinical relevanceFollowing IV co‐administration, MK‐467 effectively attenuated dexmedetomidine‐induced cardiovascular effects in cats. The drug combination resulted in transient reduction in arterial blood pressure, without causing hypotension.
Source: Veterinary Anaesthesia and Analgesia - June 30, 2016 Category: Veterinary Research Authors: Bruno H Pypendop, Juhana Honkavaara, Jan E Ilkiw Tags: Research Paper Source Type: research

Electrical velocimetry for noninvasive cardiac output and stroke volume variation measurements in dogs undergoing cardiovascular surgery
Conclusions and clinical relevanceIn dogs undergoing cardiovascular surgery, EV provided accurate CO measurements compared with CIPAC, although its trending ability was poor. Further, SVV by EV, but not CVP, reliably predicted fluid responsiveness during mechanical ventilation in dogs.
Source: Veterinary Anaesthesia and Analgesia - April 30, 2016 Category: Veterinary Research Authors: Kazumasu Sasaki, Tatsushi Mutoh, Tomoko Mutoh, Ryuta Kawashima, Hirokazu Tsubone Tags: Research Paper Source Type: research