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What we learned about the role of antenatal magnesium sulfate for the prevention of cerebral palsy
Based on the convincing case control study of Nelson and Grether which suggested that the administration of magnesium sulfate to mothers prior to early preterm birth might protect their offspring from cerebral palsy, and a pilot study by John Hauth et al. at the University of Alabama at Birmingham, the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network, with co-funding from the National Institute of Neurologic Disorders and Stroke embarked on the Beneficial Effects of Antenatal Magnesium (BEAM) Trial in 1997.
Source: Seminars in Perinatology - April 21, 2016 Category: Perinatology & Neonatology Authors: Dwight J. Rouse, Deborah Hirtz, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network Source Type: research

Preeclampsia and future cardiovascular disease in women: How good are the data and how can we manage our patients?
Women with a history of preeclampsia have double the risk of future heart disease and stroke, and elevated risks of hypertension and diabetes. The American Heart Association (AHA) and the American College of Obstetrics and Gynecology now include preeclampsia as a risk factor for future cardiovascular disease (CVD) with the recommendation of obtaining a history of preeclampsia and improving lifestyle behaviors for women with such a history. Research has progressed from asking whether preeclampsia is associated with CVD to how preeclampsia is associated with CVD, and the implications for prevention of CVD among women with a ...
Source: Seminars in Perinatology - June 24, 2015 Category: Perinatology & Neonatology Authors: Ellen Seely, Eleni Tsigas, Janet W. Rich-Edwards Source Type: research

MRI for neurodevelopmental prognostication in the high-risk term infant
MRI performed in the neonatal period has become a tool widely used by clinicians and researchers to evaluate the developing brain. MRI can provide detailed anatomical resolution, enabling identification of brain injuries due to various perinatal insults. This review will focus on the link between neonatal MRI findings and later neurodevelopmental outcomes in high-risk term infants. In particular, the role of conventional and advanced MR imaging in prognosticating outcomes in neonates with hypoxic–ischemic encephalopathy, ischemic perinatal stroke, need for extracorporeal membrane oxygenation life support, congenital hear...
Source: Seminars in Perinatology - February 21, 2015 Category: Perinatology & Neonatology Authors: An N. Massaro Source Type: research

Seizures in pregnancy: Epilepsy, eclampsia, and stroke
Abstract: Seizures during pregnancy complicate
Source: Seminars in Perinatology - August 1, 2013 Category: Perinatology & Neonatology Authors: Laura A. Hart, Baha M. Sibai Source Type: research