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The mechanisms responsible for exercise intolerance in early-stage breast cancer: What role does chemotherapy play?
Publication date: June 2013 Source:Hong Kong Physiotherapy Journal, Volume 31, Issue 1 Author(s): Alis Bonsignore , Darren Warburton In this narrative review of the literature, we discuss the influence of chemotherapy treatment on peak aerobic power (VO2peak) for women with breast cancer and the mechanisms for exercise intolerance. In specific, we examine the central, peripheral, and oxygen transport mechanisms responsible for exercise intolerance in women living with breast cancer. Our findings indicate that reduced ventricular contractility, reduced left ventricular (LV) compliance, and increased afterload are (in part...
Source: Hong Kong Physiotherapy Journal - October 12, 2014 Category: Physiotherapy Source Type: research