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Calcium supplements associated with increased risk of cardiovascular death in men but not women
Commentary on: Xiao Q, Murphy RA, Houston DK, et al.. Dietary and supplemental calcium intake and cardiovascular disease mortality: the National Institutes of Health-AARP diet and health study. JAMA Intern Med 2013;173:639–46 Implications for practice and research Calcium supplements increase cardiovascular risk. The role of calcium supplements in the management of osteoporosis should be reconsidered. Context In 2008, a randomised controlled trial (RCT) suggested that calcium supplements might increase the risk of cardiovascular events.1 Subsequent meta-analyses of RCTs examining calcium monotherapy and calcium and v...
Source: Evidence-Based Nursing - June 17, 2014 Category: Nursing Authors: Bolland, M. J., Grey, A. Tags: Primary health care, Drugs: cardiovascular system, Stroke, Diet, Ischaemic heart disease, Osteoporosis Source Type: research

Daily calcium intake in excess of 1400 mg is associated with increased all-cause and cardiovascular disease mortality in women
Commentary on: Michaëlsson K, Melhus H, Warensjö Lemming E, et al.. Long term calcium intake and rates of all cause and cardiovascular mortality: community based prospective longitudinal cohort study. BMJ 2013;346:f228. Implications for practice and research Greater calcium intake is encouraged for bone health, but has unclear cardiovascular consequences. In a large cohort of Swedish women, total calcium intake of <600 or ≥1400 mg/day was associated with an increased risk of total mortality (TM) and cardiovascular disease mortality (CVDM). It is important to emphasise adequate dietary calcium intake in...
Source: Evidence-Based Nursing - March 14, 2014 Category: Nursing Authors: Sesso, H. D., Wang, L. Tags: Drugs: cardiovascular system, Stroke, Diet, Breast cancer, Ischaemic heart disease, Clinical diagnostic tests Primary healthcare Source Type: research

Malignant Hyperthermia: A Killer If Ignored
J Perianesth Nurs. 2022 Apr 9:S1089-9472(21)00353-1. doi: 10.1016/j.jopan.2021.08.018. Online ahead of print.ABSTRACTMalignant hypothermia (MH) is a potentially fatal hypermetabolic reaction of skeletal muscle. It is an autosomal dominant disorder that generally occurs in people with RYR1, CACNA1S, or STAC3 mutations. And these genetic abnormalities often cause the imperfection of calcium release channels of skeletal muscle. The incidence of MH among different racial groups across the world ranges from approximately 1:5,000-1:250,000, but there is no national statistic MH incidence in China. It is not clear whether there a...
Source: Journal of Perianesthesia Nursing - April 13, 2022 Category: Nursing Authors: Xin Bin Baisheng Wang Zhangui Tang Source Type: research