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Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? No
ConclusionCurrent evidence does not support the notion that misclassification threatens the validity of recent case –control studies investigating the relationship between CMT and VAD. Hence, the recent re-analysis cannot refute the conclusion from previous studies that CMT is not a cause of VAD.
Source: Chiropractic and Manual Therapies - November 4, 2016 Category: Complementary Medicine Source Type: research

Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? Yes
ConclusionThere are several methodological challenges to understanding the association between neck manipulation and vertebral artery dissection. Addressing these issues is critical because even a modest association between neck manipulation and cervical artery dissection could translate into a significant number of avoidable dissections given the widespread use of neck manipulation by providers from various backgrounds. We believe that valid case classification, accurate measurement of manipulative procedures, and addressing reverse causation bias should be top priorities for future research.
Source: Chiropractic and Manual Therapies - November 4, 2016 Category: Complementary Medicine Source Type: research

Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? No
The purported relationship between cervical manipulative therapy (CMT) and stroke related to vertebral artery dissection (VAD) has been debated for several decades. A large number of publications, from case re...
Source: Chiropractic and Osteopathy - November 5, 2016 Category: Complementary Medicine Authors: Donald R. Murphy, Michael J. Schneider, Stephen M. Perle, Christopher G. Bise, Michael Timko and Mitchell Haas Source Type: research

Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? Yes
For patients and health care providers who are considering spinal manipulative therapy of the neck, it is crucial to establish if it is a trigger for cervical artery dissection and/or stroke, and if it is, the...
Source: Chiropractic and Osteopathy - November 5, 2016 Category: Complementary Medicine Authors: Jessica K. Paulus and David E. Thaler Source Type: research

The Association Between Cervical Spine Manipulation and Carotid Artery Dissection: A Systematic Review of the Literature
Controversy surrounds the safety of cervical spine manipulation. Ischemic stroke secondary to cervical spine manipulation is a hypothesized adverse event. In Canada, the seriousness of these events and their perceived association to cervical spine manipulation has led some members of the public to call for a ban of the procedure. The primary objective of this study was to determine the incidence of internal carotid artery (ICA) dissection after cervical spine manipulation in patients who experience neck pain and its associated disorders.
Source: Journal of Manipulative and Physiological Therapeutics - January 6, 2014 Category: Complementary Medicine Authors: Chadwick L.R. Chung, Pierre Côté, Paula Stern, Georges L'Espérance Source Type: research