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Teaching NeuroImages: Drug-induced parkinsonism with asymmetrical putaminal DaT binding
A 64-year-old patient developed shuffling gait and postural instability over 8 months, in parallel to risperidone intake. Examination showed symmetric parkinsonian syndrome and mild left hemiparesis with spasticity, related to right middle cerebral artery stroke 10 years before. Within 1 month of risperdone withdrawal, parkinsonism disappeared, confirming drug-induced etiology. While degenerative parkinsonism is associated with reduction in striatal dopamine transporters binding in absence of structural lesions to basal ganglia, binding in drug-induced parkinsonism is normal.1 In our case, SPECT anomaly was incidental, rel...
Source: Neurology - May 18, 2015 Category: Neurology Authors: Bridel, C., Garibotto, V. Tags: MRI, SPECT, Parkinson's disease/Parkinsonism, Basal ganglia RESIDENT AND FELLOW SECTION Source Type: research