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Therapy: Transfusion Therapy
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Total 308 results found since Jan 2013.
Red cell transfusion and alloimmunization in sickle cell disease
Haematologica. 2021 Apr 1. doi: 10.3324/haematol.2020.270546. Online ahead of print.ABSTRACTRed cell transfusion remains a critical component of care for acute and chronic complications of sickle cell disease. Randomized clinical trials demonstrated the benefits of transfusion therapy for prevention of primary and secondary strokes and postoperative acute chest syndrome. Transfusion for splenic sequestration, acute chest syndrome, and acute stroke are guided by expert consensus recommendations. Despite overall improvements in blood inventory safety, adverse effects of transfusion are prevalent among patients with sickle ce...
Source: Haematologica - April 1, 2021 Category: Hematology Authors: Grace E Linder Stella T Chou Source Type: research
Indications for transfusion in the management of sickle cell disease
Hematology Am Soc Hematol Educ Program. 2021 Dec 10;2021(1):696-703. doi: 10.1182/hematology.2021000307.ABSTRACTThe transfusion of red blood cells (RBCs) is a crucial treatment for sickle cell disease (SCD). While often beneficial, the frequent use of transfusions is associated with numerous complications. Transfusions should be offered with specific guidelines in mind. Here we present updates to the indications for transfusion of RBCs in SCD. We review recent publications and include expert perspectives from hematology and transfusion medicine. For some clinical indications, such as ischemic stroke, the role of transfusio...
Source: Hematology ASH Education Program - December 10, 2021 Category: Hematology Authors: Hyojeong Han Lisa Hensch Ven ée N Tubman Source Type: research
