Filtered By:
Specialty: Hematology
Source: Thrombosis and Haemostasis
This page shows you your search results in order of relevance. This is page number 9.
Order by Relevance | Date
Total 528 results found since Jan 2013.
Spatiotemporal profile of neutrophil extracellular trap formation in a mouse model of ischemic stroke
CONCLUSION: This study identified the spatiotemporal profile of NET formation in a mouse model of cerebral I/R injury in ischemic stroke. NETs, potentially in combination with VWF, might be attractive targets for the development of novel therapeutic strategies in ischemic stroke treatment.PMID:36852112 | PMC:PMC9958086 | DOI:10.1016/j.rpth.2022.100028
Source: Thrombosis and Haemostasis - February 28, 2023 Category: Hematology Authors: Maaike De Wilde Linda Desender Claudia Tersteeg Karen Vanhoorelbeke Simon F De Meyer Source Type: research
Protocol for a Systematic Review and Individual Participant Data Meta-Analysis of Randomized Trials of Screening for Atrial Fibrillation to Prevent Stroke
Thromb Haemost. 2023 Mar;123(3):366-376. doi: 10.1055/s-0042-1760257. Epub 2023 Mar 2.ABSTRACTINTRODUCTION: Atrial fibrillation (AF) is a common cause of stroke. Timely diagnosis of AF and treatment with oral anticoagulation (OAC) can prevent up to two-thirds of AF-related strokes. Ambulatory electrocardiographic (ECG) monitoring can identify undiagnosed AF in at-risk individuals, but the impact of population-based ECG screening on stroke is uncertain, as ongoing and published randomized controlled trials (RCTs) have generally been underpowered for stroke.METHODS AND ANALYSIS: The AF-SCREEN Collaboration, with support from...
Source: Thrombosis and Haemostasis - March 2, 2023 Category: Hematology Authors: AF SCREEN and AFFECT-EU Collaborators Source Type: research
Spatiotemporal profile of neutrophil extracellular trap formation in a mouse model of ischemic stroke
CONCLUSION: This study identified the spatiotemporal profile of NET formation in a mouse model of cerebral I/R injury in ischemic stroke. NETs, potentially in combination with VWF, might be attractive targets for the development of novel therapeutic strategies in ischemic stroke treatment.PMID:36852112 | PMC:PMC9958086 | DOI:10.1016/j.rpth.2022.100028
Source: Thrombosis and Haemostasis - February 28, 2023 Category: Hematology Authors: Maaike De Wilde Linda Desender Claudia Tersteeg Karen Vanhoorelbeke Simon F De Meyer Source Type: research
Protocol for a Systematic Review and Individual Participant Data Meta-Analysis of Randomized Trials of Screening for Atrial Fibrillation to Prevent Stroke
Thromb Haemost. 2023 Mar;123(3):366-376. doi: 10.1055/s-0042-1760257. Epub 2023 Mar 2.ABSTRACTINTRODUCTION: Atrial fibrillation (AF) is a common cause of stroke. Timely diagnosis of AF and treatment with oral anticoagulation (OAC) can prevent up to two-thirds of AF-related strokes. Ambulatory electrocardiographic (ECG) monitoring can identify undiagnosed AF in at-risk individuals, but the impact of population-based ECG screening on stroke is uncertain, as ongoing and published randomized controlled trials (RCTs) have generally been underpowered for stroke.METHODS AND ANALYSIS: The AF-SCREEN Collaboration, with support from...
Source: Thrombosis and Haemostasis - March 2, 2023 Category: Hematology Authors: AF SCREEN and AFFECT-EU Collaborators Source Type: research
Patient's values and preferences for stroke prevention in atrial fibrillation: balancing stroke and bleeding risk with oral anticoagulation.
PMID: 24477628 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - January 30, 2014 Category: Hematology Authors: Lane DA, Lip GY Tags: Thromb Haemost Source Type: research
Gaps in translation from trials to practice: Non-vitamin K antagonist oral anticoagulants (NOACs) for stroke prevention in atrial fibrillation.
The objectives of this review are to 1) identify gaps in our current knowledge regarding use of these single target anticoagulant drugs; 2) outline the potential implications of these gaps for clinical practice, and thereby, 3) highlight areas of research to further optimise their use for stroke prevention in AF.
PMID: 24573511 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - February 27, 2014 Category: Hematology Authors: Hylek EM, Ko D, Cove CL Tags: Thromb Haemost Source Type: research
Elevated levels of D-dimers increase the risk of ischaemic and haemorrhagic stroke. Findings from the EPICOR Study.
In conclusion, our data provide clear evidence that elevated levels of D-dimers are potential risk factors not only for ischaemic but also for haemorrhagic strokes.
PMID: 25030937 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - July 17, 2014 Category: Hematology Authors: Di Castelnuovo A, Agnoli C, de Curtis A, Giurdanella MC, Sieri S, Mattiello A, Matullo G, Panico S, Sacerdote C, Tumino R, Vineis P, de Gaetano G, Donati MB, Iacoviello L Tags: Thromb Haemost Source Type: research
Risk of ischaemic stroke associated with non-steroidal antiinflammatory drugs and paracetamol: a population-based case-control study.
CONCLUSIONS: Diclofenac and aceclofenac increase the risk of ischaemic stroke while ibuprofen and naproxen do not. Dose, duration and baseline CV risk, but not aspirin use, appear to modulate the risk. Paracetamol does not increase the risk, even in patients at high background CV risk. This article is protected by copyright. All rights reserved.
PMID: 25611553 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - January 22, 2015 Category: Hematology Authors: García-Poza P, de Abajo FJ, Gil MJ, Chacón A, Bryant V, García-Rodríguez LA Tags: J Thromb Haemost Source Type: research
Hemostasis Biomarkers and Risk of Sepsis: the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort.
CONCLUSION: Baseline fibrinogen, factor IX, and factor XI are associated with future episodes of sepsis. Hemostasis biomarkers may provide targets for sepsis mitigation or prevention. This article is protected by copyright. All rights reserved.
PMID: 27512924 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - August 10, 2016 Category: Hematology Authors: Moore JX, Zakai NA, Mahalingam M, Griffin RL, Irvin MR, Safford MM, Baddley JW, Wang HE Tags: J Thromb Haemost Source Type: research
Fibrin clot characteristics in acute ischaemic stroke patients treated with thrombolysis: the impact on clinical outcome.
In conclusion, formation of denser fibrin clots displaying impaired lysability and pattern of their changes induced by thrombolysis may affect clinical outcome in AIS patients.
PMID: 28382369 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - April 6, 2017 Category: Hematology Authors: Bembenek JP, Niewada M, Siudut J, Plens K, Członkowska A, Undas A Tags: Thromb Haemost Source Type: research
Interactive Effects of a Combination of the HDAC3 and HDAC9 Genes with Diabetes Mellitus on the Risk of Ischemic Stroke.
CONCLUSION: Our results suggested that the combination of the HDAC3 and HDAC9 genes with a history of diabetes mellitus could exacerbate the deterioration of atherosclerosis, thereby increasing the risk of IS. Further studies are warranted to explore our results in other populations.
PMID: 32961570 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - September 21, 2020 Category: Hematology Authors: Chiou HY, Bai CH, Lien LM, Hu CJ, Jeng JS, Tang SC, Lin HJ, Hsieh YC Tags: Thromb Haemost Source Type: research
Stroke and Thromboembolism in Warfarin-Treated Patients with Atrial Fibrillation: Comparing the CHA2DS2-VASc and GARFIELD-AF Risk Scores.
CONCLUSIONS: In a warfarin-treated trial cohort of AF patients, both CHA2DS2-VASc and GARFIELD-AF Stroke scores were associated with adjudicated TE events, with modest predictive capacity. Simpler CHA2DS2-VASc score improved discriminatory capacity compared to more complex GARFIELD-AF score, demonstrating improved clinical usefulness and net clinical benefit.
PMID: 33296920 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - December 9, 2020 Category: Hematology Authors: Proietti M, Rivera-Caravaca JM, Esteve-Pastor MA, Marín F, Lip GY Tags: Thromb Haemost Source Type: research
An older thrombus delays reperfusion after mechanical thrombectomy for ischemic stroke
CONCLUSIONS: An older thrombus delays reperfusion after mechanical thrombectomy for ischemic stroke. Adding therapies targeting thrombus maturation may improve the efficacy of mechanical thrombectomy.PMID:34077976 | DOI:10.1055/a-1522-4507
Source: Thrombosis and Haemostasis - June 2, 2021 Category: Hematology Authors: Takaya Kitano Yumiko Hori Shuhei Okazaki Yuki Shimada Takanori Iwamoto Hideaki Kanki Shintaro Sugiyama Tsutomu Sasaki Hajime Nakamura Naoki Oyama Taku Hoshi Goichi Beck Hiroki Takai Shunji Matsubara Hiroya Mizuno Hirotake Nishimura Ryo Tamaki Junichi Iida Source Type: research
Anticoagulation use and the risk of stroke and major bleeding in patients on hemodialysis: From the VIVALDI, a population-based prospective cohort study
CONCLUSIONS: Although the non-randomized nature of the study is prone to bias, anticoagulation with VKA was not associated with decreased thromboembolic risk, but associated with increased risk of major bleeding and may be net-harmful to patients with AF on HD.PMID:34418291 | DOI:10.1111/jth.15508
Source: Thrombosis and Haemostasis - August 21, 2021 Category: Hematology Authors: Oliver K önigsbrügge Hannah Meisel Aljoscha Beyer Sabine Schmaldienst Renate Klauser-Braun Matthias Lorenz Martin Auinger Josef Kletzmayr Manfred Hecking Wolfgang C Winkelmayer Irene Lang Ingrid Pabinger Marcus S äemann Cihan Ay Source Type: research
