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Intravenous Thrombolysis Resulting In Acute Ischemic Stroke Recanalization Can Lead To Cerebral Hyperperfusion Syndrome (P7.123)
Conclusion- Cerebral hyperperfusion syndrome after intravenous thrombolysis in acute ischemic stroke should be suspected in patients that achieve arterial recanalization and develop unexplained new neuropsychiatric manifestations.Disclosure: Dr. Ong has nothing to disclose. Dr. Yeo has nothing to disclose. Dr. Ting has nothing to disclose. Dr. Sinha has nothing to disclose. Dr. Teoh has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Seet has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ong, J., Yeo, L., Ting, E., Sinha, A., Teoh, H. L., Chan, B., Seet, C. S., Sharma, V. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment Source Type: research

Hyperdopaminergism in Lenticulostriate Stroke-Induced Restless Legs Syndrome: A Neuro Imaging Study (P7.303)
CONCLUSIONS: A systematic study of small lesions associated with RLS may contribute to understanding the pathophysiological mechanisms underlying this condition. In this regard, the body of the caudate nucleus might be an important structure. The isotopic results reinforce the hypothesis of an increased dopaminergic tone in the striatum as part of RLS pathophysiology. Thus, the efficacy with low doses of dopaminergic agonists in RLS could be explained by stimulation of inhibitory D2-like autoreceptors.Disclosure: Dr. Ruppert has nothing to disclose. Dr. Bataillard has nothing to disclose. Dr. Namer has nothing to disclose....
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ruppert, E., Bataillard, M., Namer, I., Tatu, L., Wolff, V., Velizarova, R., Hacquard, A., Killic-Huck, U., Bourgin, P. Tags: Sleep: Restless Legs and REM Disorders Source Type: research

Correlation of Transcranial Doppler Breath Holding Test and Acetazolamide SPECT Scan for Anterior Circulation Steno-Occlusive Disease (P6.019)
Conclusions: There was a modest correlation between TCD-R and acetazolamide SPECT scan for anterior circulation steno-occlusive disease in our patient cohort. TCD-R demonstrated higher sensitivity for the detection of poor cerebrovascular reserve than acetazolamide SPECT. Further studies are needed to determine which study is more useful in the management of this high-risk population. Disclosure: Dr. Parikh has nothing to disclose. Dr. Cerejo has nothing to disclose. Dr. Raber has nothing to disclose. Dr. Thompson has nothing to disclose. Dr. Uchino has nothing to disclose. Dr. Katzan has received personal compensation f...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Parikh, P., Cerejo, R., Raber, L., Thompson, N., Uchino, K., Katzan, I. Tags: Ischemic Stroke Diagnosis Source Type: research

Susceptibility Weighted MRI and Regional Cerebrovascular Reservoir Capacity in Angiography Proven Large Artery Disease in Acute Ischemic Stroke and Transient Ischemic Attack (P6.247)
CONCLUSIONS:Cortical vessel signs on susceptibility-weighted image have an association with regional cerebrovascular reservoir capacity. And this snapshout image would be a useful tool in the real world of clinical practice in evaluating cerebrovascular perfusion status. But longer follow up in much larger populations are needed.Disclosure: Dr. Lee has nothing to disclose. Dr. Won has nothing to disclose. Dr. Yoo has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Lee, S. B., Won, Y. D., Yoo, D.-S. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research

Neuro-Behcet's Syndrome:Case Reports Emphasizing Challenges of Early Diagnosis (P2.075)
CONCLUSIONS: In both cases, NBS was ultimately diagnosed based on characteristic MRI findings, particularly fluctuating brain stem-diencephalic involvement, superimposed on supportive clinical and CSF profiles. Challenges to early diagnosis are highlighted by our cases and by the literature. The differential diagnosis is often broad at onset. Mucocutaenous symptoms can be a clue but may not be present. Awareness of NBS and its neuroimaging correlates is critical to enable timely diagnosis, particularly given that this condition can favorably respond to steroids and steroid-sparing agents.Disclosure: Dr. Feldman has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Feldman, E. Tags: Neurological Consequences of Autoimmune Disease Source Type: research

Teaching NeuroImages: Drug-induced parkinsonism with asymmetrical putaminal DaT binding
A 64-year-old patient developed shuffling gait and postural instability over 8 months, in parallel to risperidone intake. Examination showed symmetric parkinsonian syndrome and mild left hemiparesis with spasticity, related to right middle cerebral artery stroke 10 years before. Within 1 month of risperdone withdrawal, parkinsonism disappeared, confirming drug-induced etiology. While degenerative parkinsonism is associated with reduction in striatal dopamine transporters binding in absence of structural lesions to basal ganglia, binding in drug-induced parkinsonism is normal.1 In our case, SPECT anomaly was incidental, rel...
Source: Neurology - May 18, 2015 Category: Neurology Authors: Bridel, C., Garibotto, V. Tags: MRI, SPECT, Parkinson's disease/Parkinsonism, Basal ganglia RESIDENT AND FELLOW SECTION Source Type: research

Abnormal neurovascular coupling during status epilepticus migrainosus in Sturge-Weber syndrome
Sturge-Weber syndrome is a rare, sporadic, neurocutaneous disorder classically characterized by a facial nevus in the trigeminal distribution (port wine stain), leptomeningeal angiomatosis, and glaucoma, although intracranial changes can be present without cutaneous involvement.1 Seizures occur in up to 75% of individuals, are often associated with headache, and stroke-like episodes causing prolonged neurologic deficits are also described.1,2
Source: Neurology - January 8, 2017 Category: Neurology Authors: Sethi, M., Kowalczyk, M. A., Dalic, L. J., Archer, J. S., Jackson, G. D. Tags: Migraine, Status epilepticus, Functional neuroimaging, PET in epilepsy, SPECT in epilepsy CLINICAL/SCIENTIFIC NOTES Source Type: research