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Cardiovascular and respiratory effects of carbon dioxide pneumoperitoneum in the domestic rabbit (Oryctolagus cuniculus).
In conclusion, pneumoperitoneum with carbon dioxide causes an increase in ETCO2, PaCO2, and PIP, whereas cardiac output and CI decrease. These cardiorespiratory changes should be considered when determining the optimal IAP for laparoscopic procedures in rabbits. PMID: 32255905 [PubMed - in process]
Source: Canadian Journal of Veterinary Research - March 31, 2020 Category: Veterinary Research Authors: Kabakchiev C, Valverde A, Singh A, Beaufrère H Tags: Can J Vet Res Source Type: research

Predictive values of pulse pressure variation and stroke volume variation for fluid responsiveness in patients with pneumoperitoneum
AbstractAnimal studies suggest that dynamic predictors remain useful in patients with pneumoperitoneum, but human data is conflicting. Our aim was to determine predictive values of pulse pressure variation (PPV) and stroke volume variation (SVV) in patients with pneumoperitoneum using LiDCORapid ™ haemodynamic monitor. Standardised fluid challenges of colloid were administered to patients undergoing laparoscopic procedures, one fluid challenge per patient. Intra-abdominal pressure was automatically held at 12  mmHg. Fluid responsiveness was defined as an increase in nominal stroke index (nSI) ≥ 10%. Linear regress...
Source: Journal of Clinical Monitoring and Computing - October 1, 2018 Category: Information Technology Source Type: research