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Source: Stroke

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Total 4002 results found since Jan 2013.

Influence of Distance to Scene on Time to Thrombolysis in a Specialized Stroke Ambulance Brief Reports
Conclusions— In a metropolitan area such as Berlin, time benefits justify a specialized stroke ambulance service up to a mean travel time of 18 minutes from base station. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT01382862.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Koch, P. M., Kunz, A., Ebinger, M., Geisler, F., Rozanski, M., Waldschmidt, C., Weber, J. E., Wendt, M., Winter, B., Zieschang, K., Bollweg, K., Kaczmarek, S., Endres, M., Audebert, H. J. Tags: Health Services, Quality and Outcomes, Ischemic Stroke Brief Reports Source Type: research

Association of Major Depressive Episodes With Stroke Risk in a Prospective Study of 0.5 Million Chinese Adults Clinical Sciences
Conclusions— Findings from this large prospective study suggest that the presence of MDE is a risk factor for stroke, especially in smokers.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Sun, J., Ma, H., Yu, C., Lv, J., Guo, Y., Bian, Z., Yang, L., Chen, Y., Shen, H., Chen, Z., Hu, Z., Li, L., on behalf of the China Kadoorie Biobank Collaborative Group Tags: Mental Health, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Effects of Alteplase for Acute Stroke on the Distribution of Functional Outcomes: A Pooled Analysis of 9 Trials Clinical Sciences
Conclusions— Treatment with intravenous alteplase initiated within 4.5 hours of stroke onset increases the chance of achieving an improved level of function for all patients across the age spectrum, including the over 80s and across all severities of stroke studied (top versus bottom fifth means: 22 versus 4); the earlier that treatment is initiated, the greater the benefit.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Lees, K. R., Emberson, J., Blackwell, L., Bluhmki, E., Davis, S. M., Donnan, G. A., Grotta, J. C., Kaste, M., von Kummer, R., Lansberg, M. G., Lindley, R. I., Lyden, P., Murray, G. D., Sandercock, P. A. G., Toni, D., Toyoda, K., Wardlaw, J. M., Whiteley, Tags: Treatment, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Clinical Sciences Source Type: research

Parental Care-Seeking Behavior and Prehospital Timelines of Care in Childhood Arterial Ischemic Stroke Brief Reports
Conclusions— Stroke recognition and care-seeking behavior are suboptimal, with less than half the parents considering stroke or calling an ambulance. Initiatives are required to educate parents about appropriate actions to facilitate time-critical interventions.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Mackay, M. T., Stojanovski, B., Mosley, I., Churilov, L., Donnan, G. A., Monagle, P. Tags: Pediatrics, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Coexistent Sickle Cell Disease Has No Impact on the Safety or Outcome of Lytic Therapy in Acute Ischemic Stroke Clinical Sciences
Conclusions—Coexistent SCD had no significant impact on the safety or outcome of thrombolytic therapy in acute ischemic stroke. Although the sample size is relatively small, these data suggest that adults with SCD and acute ischemic stroke should be treated with thrombolysis, if they otherwise qualify. Addition studies, however, should track the intracranial hemorrhage rate and provide information on other SCD-related care such as transfusion.
Source: Stroke - February 26, 2017 Category: Neurology Authors: Robert J. Adams, Margueritte Cox, Shelly D. Ozark, Julie Kanter, Phillip J. Schulte, Ying Xian, Gregg C. Fonarow, Eric E. Smith, Lee H. Schwamm Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Development and Validation of a Bilingual Stroke Preparedness Assessment Instrument Clinical Sciences
Background and Purpose—Stroke preparedness interventions are limited by the lack of psychometrically sound intermediate end points. We sought to develop and assess the reliability and validity of the video-Stroke Action Test (video-STAT) an English and a Spanish video-based test to assess people’s ability to recognize and react to stroke signs.Methods—Video-STAT development and testing was divided into 4 phases: (1) video development and community-generated response options, (2) pilot testing in community health centers, (3) administration in a national sample, bilingual sample, and neurologist sample, and (4) admini...
Source: Stroke - March 27, 2017 Category: Neurology Authors: Lesli E. Skolarus, Kathleen M. Mazor, Brisa N. Sanchez, Mackenzie Dome, Jose Biller, Lewis B. Morgenstern Tags: Health Services, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Homocysteine and Stroke Risk Clinical Sciences
Conclusions—In Chinese hypertensive patients, the effect of homocysteine on the first stroke was significantly modified by the methylenetetrahydrofolate reductase C677T genotype and folic acid supplementation. Such information may help to more precisely predict stroke risk and develop folic acid interventions tailored to individual genetic background and nutritional status.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00794885.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Min Zhao, Xiaobin Wang, Mingli He, Xianhui Qin, Genfu Tang, Yong Huo, Jianping Li, Jia Fu, Xiao Huang, Xiaoshu Cheng, Binyan Wang, Fan Fan Hou, Ningling Sun, Yefeng Cai Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

The FAST-ED App: A Smartphone Platform for the Field Triage of Patients With Stroke Clinical Sciences
Conclusions—The FAST-ED smartphone application has great potential to improve the triage of patients with acute ischemic stroke, as it seems capable to optimize resources, reduce hospital arrivals times, and maximize the use of both intravenous tissue-type plasminogen activator and endovascular treatment ultimately leading to better clinical outcomes. Future field studies are needed to properly evaluate the impact of this tool in stroke outcomes and resource utilization.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Raul G. Nogueira, Gisele S. Silva, Fabricio O. Lima, Yu-Chih Yeh, Carol Fleming, Daniel Branco, Arthur H. Yancey, Jonathan J. Ratcliff, Robert Keith Wages, Earnest Doss, Mehdi Bouslama, Jonathan A. Grossberg, Diogo C. Haussen, Teppei Sakano, Michael R. Fr Tags: Quality and Outcomes, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

CHA2DS2-VASc Score (Congestive Heart Failure, Hypertension, Age >=75 Doubled, Diabetes Mellitus, Prior Stroke or Transient Ischemic Attack Doubled, Vascular Disease, Age 65-74, Female) for Stroke in Asian Patients With Atrial Fibrillation Clinical Sciences
Background and Purpose—The CHA2DS2-VASc stroke score (congestive heart failure, hypertension, age ≥75 (doubled), diabetes mellitus, prior stroke or transient ischemic attack (doubled), vascular disease, age 65–74, female) is used in most guidelines for risk stratification in atrial fibrillation (AF), but most data for this score have been derived in Western populations. Ethnic differences in stroke risk may be present. Our objective was to investigate risk factors for stroke in AF and application of the CHA2DS2-VASc score in an Asian AF population from Korea.Methods—A total of 5855 oral anticoagulant–naive nonval...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Tae-Hoon Kim, Pil-Sung Yang, Jae-Sun Uhm, Jong-Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y.H. Lip Tags: Arrhythmias, Risk Factors, Ischemic Stroke Original Contributions Source Type: research

Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke Clinical Sciences
We examined prospectively the association between serum IGF-1 levels and incident ischemic stroke.Methods—We measured serum IGF-1 levels in 757 elderly individuals (mean age 79±5, 62% women), free of prevalent stroke, from the Framingham original cohort participants at the 22nd examination cycle (1990–1994) and were followed up for the development of ischemic stroke. Cox models were used to relate IGF-1 levels to the risk for incident ischemic stroke, adjusted for potential confounders.Results—During a mean follow-up of 10.2 years, 99 individuals developed ischemic stroke. After adjustment for age, sex, and potentia...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Hamidreza Saber, Jayandra J. Himali, Alexa S. Beiser, Ashkan Shoamanesh, Aleksandra Pikula, Ronenn Roubenoff, Jose R. Romero, Carlos S. Kase, Ramachandran S. Vasan, Sudha Seshadri Tags: Risk Factors, Ischemic Stroke Original Contributions Source Type: research

Statin Adherence Is Associated With Reduced Recurrent Stroke Risk in Patients With or Without Atrial Fibrillation Clinical Sciences
Conclusions—The relationship between statin adherence and reduced recurrent stroke risk is as strong among patients with AFib as it is among patients without AFib, suggesting that AFib status should not be a reason to exclude patients from secondary stroke prevention with a statin.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Alexander C. Flint, Carol Conell, Xiushui Ren, Hooman Kamel, Sheila L. Chan, Vivek A. Rao, S. Claiborne Johnston Tags: Arrhythmias, Lipids and Cholesterol, Secondary Prevention, Ischemic Stroke Original Contributions Source Type: research

Optimal Transport Destination for Ischemic Stroke Patients With Unknown Vessel Status Clinical Sciences
Conclusions—Use of RACE cutoff scores that take into account transport times to triage AIS patients to the nearest appropriate hospital may lead to improved outcomes. Further studies should examine the feasibility of translation into clinical practice.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Eckhard Schlemm, Martin Ebinger, Christian H. Nolte, Matthias Endres, Ludwig Schlemm Tags: Revascularization, Health Services, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Trajectories in Leisure-Time Physical Activity and Risk of Stroke in Women in the California Teachers Study Clinical Sciences
Conclusions—Meeting AHA recommendations for moderate activity had a protective effect for reducing ischemic stroke risk. Participants who met AHA recommendations at baseline but not at follow-up, however, were not afforded reduced stroke risk.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Joshua Z. Willey, Jenna Voutsinas, Ayesha Sherzai, Huiyan Ma, Leslie Bernstein, Mitchell S.V. Elkind, Ying K. Cheung, Sophia S. Wang Tags: Lifestyle, Primary Prevention, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Cerebral Microbleeds and the Risk of Incident Ischemic Stroke in CADASIL (Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy) Clinical Sciences
Conclusions—The presence of microbleeds is an independent risk marker of incident ischemic stroke in CADASIL, emphasizing the need to carefully interpret MRI data.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Laurent Puy, Francois De Guio, Ophelia Godin, Marco Duering, Martin Dichgans, Hugues Chabriat, Eric Jouvent Tags: Magnetic Resonance Imaging (MRI), CADASIL, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Dietary Sodium to Potassium Ratio and Risk of Stroke in a Multiethnic Urban Population Clinical Sciences
Conclusions—Na:K intake is an independent predictor of stroke risk. Further studies are required to understand the joint effect of Na and K intake on risk of cardiovascular disease.
Source: Stroke - October 23, 2017 Category: Neurology Authors: Joshua Willey, Hannah Gardener, Sandino Cespedes, Ying K. Cheung, Ralph L. Sacco, Mitchell S.V. Elkind Tags: Diet and Nutrition, Epidemiology, Risk Factors, Ischemic Stroke Original Contributions Source Type: research