• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Imaging the collaterome: a stroke renaissance
No abstract available
Source: Current Opinion in Neurology - January 6, 2015 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by David S. Liebeskind Source Type: research

Mechanisms of sudden unexplained death in epilepsy
Purpose of review: Human and experimental research has identified cardioautonomic and respiratory dysfunction as a frequent accompaniment in human and animal model events of sudden unexpected death in epilepsy (SUDEP). This review aims to provide an overview of the scientific evidence behind the currently accepted risk factors and working hypotheses regarding SUDEP pathophysiology. Recent findings: Epidemiological analysis of public health burden of SUDEP has shown that it rates second only to stroke in the years of potential life lost. Clinical and experimental studies uncovered the dynamic cardiorespiratory dysfunction i...
Source: Current Opinion in Neurology - March 5, 2015 Category: Neurology Tags: SEIZURE DISORDERS: Edited by Michael R. Sperling Source Type: research

Stroke: two steps forward, one step sideward
No abstract available
Source: Current Opinion in Neurology - January 12, 2016 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Patrik Michel Source Type: research

Real-time functional magnetic resonance imaging neurofeedback in motor neurorehabilitation
Purpose of review: Recent developments in functional magnetic resonance imaging (fMRI) have catalyzed a new field of translational neuroscience. Using fMRI to monitor the aspects of task-related changes in neural activation or brain connectivity, investigators can offer feedback of simple or complex neural signals/patterns back to the participant on a quasireal-time basis [real-time-fMRI-based neurofeedback (rt-fMRI-NF)]. Here, we introduce some background methodology of the new developments in this field and give a perspective on how they may be used in neurorehabilitation in the future. Recent findings: The development ...
Source: Current Opinion in Neurology - July 2, 2016 Category: Neurology Tags: NEUROIMAGING: Edited by Stefan Kloppel Source Type: research

A new neuroinformatics approach to personalized medicine in neurology: The Virtual Brain
Purpose of review: An exciting advance in the field of neuroimaging is the acquisition and processing of very large data sets (so called ‘big data’), permitting large-scale inferences that foster a greater understanding of brain function in health and disease. Yet what we are clearly lacking are quantitative integrative tools to translate this understanding to the individual level to lay the basis for personalized medicine. Recent findings: Here we address this challenge through a review on how the relatively new field of neuroinformatics modeling has the capacity to track brain network function at different levels of...
Source: Current Opinion in Neurology - July 2, 2016 Category: Neurology Tags: NEUROIMAGING: Edited by Stefan Kloppel Source Type: research

Behavioral self-management strategies for practice and exercise should be included in neurologic rehabilitation trials and care
Purpose of review: Rehabilitation trials and postacute care to lessen impairments and disability after stroke, spinal cord injury, and traumatic brain injury almost never include training to promote long-term self-management of skills practice, strengthening and fitness. Without behavioral training to develop self-efficacy, clinical trials, and home-based therapy may fail to show robust results. Recent findings: Behavioral theories about self-management and self-efficacy for physical activity have been successfully incorporated into interventions for chronic diseases, but rarely for neurologic rehabilitation. The elements...
Source: Current Opinion in Neurology - November 8, 2016 Category: Neurology Tags: TRAUMA AND REHABILITATION: Edited by Bruce H. Dobkin Source Type: research

The growing clinical spectrum of cerebral amyloid angiopathy
Purpose of review Cerebral amyloid angiopathy (CAA) is diagnosed primarily as a cause of lobar intracerebral hemorrhages (ICH) in elderly patients. With improving MRI techniques, however, the role of CAA in causing other symptoms has become clear. Recognizing the full clinical spectrum of CAA is important for diagnosis and treatment. In this review we summarize recent insights in clinical CAA features, MRI biomarkers, and management. Recent findings The rate of ICH recurrence in CAA is among the highest of all stroke subtypes. Cortical superficial siderosis (cSS) and cortical subarachnoid hemorrhage (cSAH) are importa...
Source: Current Opinion in Neurology - December 20, 2017 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Hugh S. Markus Source Type: research

Central control of eye movements
This article reviews recent findings in relation to saccadic eye movements, particularly antisaccades and microsaccades, with particular emphasis on the control of inaction, something which has recently become topical. Recent findings Microsaccades are under the control of the cerebral cortex, particularly the frontal and parietal eye fields. Their frequency and direction alters following presentation of visual stimuli. Spontaneous alterations in their frequency are correlated with alterations in the frequency of the gamma-band activity in the visual cortex as well as, interestingly, the heartbeat. Studies of saccades i...
Source: Current Opinion in Neurology - December 20, 2017 Category: Neurology Tags: NEURO-OPHTHALMOLOGY AND NEURO-OTOLOGY: Edited by José-Alain Sahel, Michael Strupp and David Zee Source Type: research

The growing clinical spectrum of cerebral amyloid angiopathy
Purpose of review Cerebral amyloid angiopathy (CAA) is diagnosed primarily as a cause of lobar intracerebral hemorrhages (ICH) in elderly patients. With improving MRI techniques, however, the role of CAA in causing other symptoms has become clear. Recognizing the full clinical spectrum of CAA is important for diagnosis and treatment. In this review we summarize recent insights in clinical CAA features, MRI biomarkers, and management. Recent findings The rate of ICH recurrence in CAA is among the highest of all stroke subtypes. Cortical superficial siderosis (cSS) and cortical subarachnoid hemorrhage (cSAH) are importa...
Source: Current Opinion in Neurology - January 17, 2018 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Hugh S. Markus Source Type: research

Central control of eye movements
This article reviews recent findings in relation to saccadic eye movements, particularly antisaccades and microsaccades, with particular emphasis on the control of inaction, something which has recently become topical. Recent findings Microsaccades are under the control of the cerebral cortex, particularly the frontal and parietal eye fields. Their frequency and direction alters following presentation of visual stimuli. Spontaneous alterations in their frequency are correlated with alterations in the frequency of the gamma-band activity in the visual cortex as well as, interestingly, the heartbeat. Studies of saccades i...
Source: Current Opinion in Neurology - January 17, 2018 Category: Neurology Tags: NEURO-OPHTHALMOLOGY AND NEURO-OTOLOGY: Edited by José-Alain Sahel, Michael Strupp and David Zee Source Type: research

Is intravenous thrombolysis still necessary in patients who undergo mechanical thrombectomy?
Purpose of review To summarize available evidence on the potential utility of pretreatment with intravenous thrombolysis (IVT) using recombinant tissue-plasminogen activator (rt-PA) in acute ischemic stroke (AIS) patients with large vessel occlusions (LVO) who are treated with mechanical thrombectomy. Recent findings Despite theoretical concerns of a higher bleeding risk with IVT pretreatment, there are no data showing increased risk of symptomatic intracerebral hemorrhage (sICH) in patients with LVO receiving bridging therapy (IVT and mechanical thrombectomy) compared with direct mechanical thrombectomy (dMT). Additi...
Source: Current Opinion in Neurology - January 13, 2019 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Didier Leys Source Type: research

Examining the ocular fundus in neurology
Purpose of review The funduscopic examination can be a technically difficult, and often omitted, portion of the neurologic examination, despite its great potential to influence patient care. Recent findings Medical practitioners are often first taught to examine the ocular fundus using a direct ophthalmoscope, however, this skill requires frequent practice. Nonmydriatic tabletop and portable fundus photography and even smartphone-based photography offer alternative and practical means for approaching examination of the ocular fundus. These alternative tools have been shown to be practical in a variety of settings incl...
Source: Current Opinion in Neurology - January 13, 2019 Category: Neurology Tags: NEURO-OPHTHALMOLOGY: Edited by Valérie Biousse Source Type: research

Update on obstructive sleep apnea for neuro-ophthalmology
Purpose of review Obstructive sleep apnea (OSA) is increasing in prevalence. The intermittent hypoxia of OSA has wide-ranging effects on a patient's general health outcomes. However, gold-standard investigations and treatment are expensive and a significant burden on patients. Therefore, OSA research remains focused on improving the means of diagnosing and treating OSA, in high-risk-associated conditions. This review is to provide an update on the advances in the field of OSA. Recent findings There has been recent debate about the best practice for diagnosis and treatment of OSA. Further work has been done on conditio...
Source: Current Opinion in Neurology - January 13, 2019 Category: Neurology Tags: NEURO-OPHTHALMOLOGY: Edited by Valérie Biousse Source Type: research

Novel synaptic plasticity enhancer drug to augment functional recovery with rehabilitation
Purpose of review Stroke is a devastating illness which severely attenuates quality of life because of paralysis. Despite recent advances in therapies during acute phase such as thrombolytic therapy, clinical option to intervene the process of rehabilitation is limited. No pharmacological intervention that could enhance the effect of rehabilitation has not been established. Recent articles, which are summarized in the review article, reported novel small compound which accelerates training-dependent motor function recovery after brain damage. Recent findings A novel small compound, edonerpic maleate, binds to collapsi...
Source: Current Opinion in Neurology - November 5, 2019 Category: Neurology Tags: TRAUMA AND REHABILITATION: Edited by Rajiv R. Ratan and Yutaka Yoshida Source Type: research

Editorial: Advances in understanding causes and outcomes in stroke
No abstract available
Source: Current Opinion in Neurology - January 17, 2020 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Mitchell S.V. Elkind Source Type: research

Pages: 1  2  3  4  5  6  7