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Total 262 results found since Jan 2013.

Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer
Conclusions Cancer history is linked to increased risk of incident CVDs and adverse cardiac remodelling independent of shared vascular risk factors.
Source: Heart - June 14, 2023 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., McCracken, C., Crosbie, E. J., Walter, F. M., Manisty, C. H., Robson, J., Mamas, M. A., Harvey, N. C., Neubauer, S., Petersen, S. E. Tags: Open access, Editor's choice, Press releases Cardiac risk factors and prevention Source Type: research

Exercise-induced torsional dyssynchrony relates to impaired functional capacity in patients with heart failure and normal ejection fraction
Conclusions HFNEF involves exercise-induced torsional dyssynchrony in systole and diastole, which relates to LV hypertrophy as well as exercise capacity.
Source: Heart - January 25, 2013 Category: Cardiology Authors: Tan, Y. T., Wenzelburger, F. W., Sanderson, J. E., Leyva, F. Tags: Heart failure, Drugs: cardiovascular system, Echocardiography, Hypertension, Clinical diagnostic tests Source Type: research

Arterial disease in chronic kidney disease
End stage renal disease is associated with a very high risk of premature cardiovascular death and morbidity. Early stage chronic kidney disease (CKD) is also associated with an increased frequency of cardiovascular events and is a common but poorly recognised and undertreated risk factor. Cardiovascular disease in CKD can be attributed to two distinct but overlapping pathological processes, namely atherosclerosis and arteriosclerosis. While the risk of athero-thrombotic events such as myocardial infarction is elevated, arteriosclerosis is the predominant pathophysiological process involving fibrosis and thickening of the m...
Source: Heart - February 18, 2013 Category: Cardiology Authors: Moody, W. E., Edwards, N. C., Chue, C. D., Ferro, C. J., Townend, J. N. Tags: Reviews Source Type: research

MR-proANP and MR-proADM for risk stratification of patients with acute chest pain
Conclusions MR-proADM and MR-proANP are predictors of future cardiovascular events in patients presenting with acute chest pain and might facilitate the choice of treatment in those patients complementary to established risk scores.
Source: Heart - February 18, 2013 Category: Cardiology Authors: Tzikas, S., Keller, T., Ojeda, F. M., Zeller, T., Wild, P. S., Lubos, E., Kunde, J., Baldus, S., Bickel, C., Lackner, K. J., Munzel, T. F., Blankenberg, S. Tags: Drugs: cardiovascular system, Acute coronary syndromes, Epidemiology Biomarkers and heart disease Source Type: research

Risk assessment in hypertrophic cardiomyopathy: contemporary guidelines hampered by insufficient evidence
If it were not for the great variability among individuals, medicine might as well be a science and not an art. (Sir William Osler, 1892) The sudden unexpected death of an individual at any age has a profound effect on the family and the wider community and this is particularly significant when it affects a young person. Hypertrophic cardiomyopathy remains one of the common causes of sudden cardiac death (SCD) in young individuals.1 In a cohort of 744 patients with hypertrophic cardiomyopathy from the USA and Italy, where 86 (12%) died over an 8 (SD±7) year period of follow-up, three main modes of death were identif...
Source: Heart - March 19, 2013 Category: Cardiology Authors: McKeown, P. P., Muir, A. R. Tags: Open access, Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Hypertension Editorials Source Type: research

Is C reactive protein expression affected by local microenvironment?
The role that inflammation plays on the vasculature has become fundamental in our understanding of the different steps underlying the development of coronary heart disease (CHD).1 Immunological-related inflammatory processes accompany all stages of atherosclerosis development, from the early formation of lesions in the arteries to the rupture of the atherosclerotic plaques, which leads to dramatic consequences such as myocardial infarction and stroke. In this light, the search of markers of inflammation that could help to predict and even to treat cardiovascular diseases has been the subject of intense investigation. C rea...
Source: Heart - March 19, 2013 Category: Cardiology Authors: Ummarino, D., Zeng, L. Tags: Drugs: cardiovascular system, Acute coronary syndromes, Epidemiology Editorials Source Type: research

Incidence, cardiovascular complications and mortality of hypertension by sex and ethnicity
Conclusions South Asian patients had higher rates of hypertension compared to the other ethnic groups. South Asian and Chinese patients had a lower risk of death and developing cardiovascular outcomes compared to whites. Women with hypertension have a better prognosis than men regardless of ethnicity.
Source: Heart - April 18, 2013 Category: Cardiology Authors: Quan, H., Chen, G., Walker, R. L., Wielgosz, A., Dai, S., Tu, K., Campbell, N. R. C., Hemmelgarn, B. R., Hill, M. D., Johansen, H., McAlister, F. A., Khan, N., for Hypertension Outcome and Surveillance Team Tags: Hypertension, Editor's choice, Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Epidemiology Source Type: research

Methods of accelerated atherosclerosis in diabetic patients
This article will focus on the effect of diabetes on the initiation and progression of arterial occlusive disease, preceded by a short outline of the enormous impact of this issue from a societal-economic perspective. Diabetes, a major healthcare issue The prevalence and associated costs of diabetes are expected to increase significantly. There are currently over 240...
Source: Heart - April 18, 2013 Category: Cardiology Authors: Pasterkamp, G. Tags: Diabetic heart disease, Health policy, Education in Heart, Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Stable coronary heart disease, Epidemiology, Diabetes, Metabolic disorders Source Type: research

The role of uric acid in the pathogenesis of human cardiovascular disease
Hyperuricaemia is common in subjects with cardiovascular disease, but is not commonly considered a true risk factor. Recent studies suggest that uric acid is biologically active and can stimulate oxidative stress, endothelial dysfunction, inflammation and vasoconstriction. Epidemiological studies have found that uric acid can independently predict the development of hypertension, as well as stroke and heart failure. Experimentally raising uric acid in animals increases blood pressure, and pilot studies suggest that lowering uric acid in humans can reduce blood pressure in hypertensive individuals. Uric acid may also have e...
Source: Heart - May 1, 2013 Category: Cardiology Authors: Kanbay, M., Segal, M., Afsar, B., Kang, D.-H., Rodriguez-Iturbe, B., Johnson, R. J. Tags: Reviews Source Type: research

Bilateral internal mammary artery bypass grafting: long-term clinical benefits in a series of 1000 patients
Conclusions Our longitudinal analysis presents encouraging data concerning operative risk of BIMA grafting and provides excellent long-term survival in appropriately selected patients.
Source: Heart - May 13, 2013 Category: Cardiology Authors: Popovic, B., Voillot, D., Maureira, P., Vanhuyse, F., Agrinier, N., Aliot, E., Folliguet, T., Villemot, J. P. Tags: Drugs: cardiovascular system, Interventional cardiology, Acute coronary syndromes, Epidemiology Cardiovascular surgery Source Type: research

Development and validation of a prediction rule for recurrent vascular events based on a cohort study of patients with arterial disease: the SMART risk score
Conclusions Patients at high risk for recurrent vascular events can be identified based on readily available clinical characteristics.
Source: Heart - May 13, 2013 Category: Cardiology Authors: Dorresteijn, J. A. N., Visseren, F. L. J., Wassink, A. M. J., Gondrie, M. J. A., Steyerberg, E. W., Ridker, P. M., Cook, N. R., van der Graaf, Y., on behalf of the SMART Study Group, Algra, Grobbee, Rutten, Moll, Kappelle, Mali, Doevendans Tags: Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Clinical diagnostic tests, Epidemiology, Tobacco use Prognosis research Source Type: research

The 10 'Best Buys' to combat heart disease, diabetes and stroke in Africa
The Economist has branded Africa as ‘the world's fastest growing continent’.1 The economy in many African countries is growing at a rate that is higher than that of European countries. HIV infection is coming under control and life expectancy is increasing as a result of widespread use of antiretroviral therapy.2 The rising economic prosperity and improving health status has been associated with what can be described as a renaissance in cardiovascular medicine that is characterised by the revival of pan-African professional organisations, such as the Pan African Society of Cardiology (PASCAR) and the creation o...
Source: Heart - June 26, 2013 Category: Cardiology Authors: Mayosi, B. M. Tags: Drugs: cardiovascular system, Hypertension, Acute coronary syndromes, Epidemiology Editorials Source Type: research

Alcohol intake and prognosis of atrial fibrillation
Conclusions High alcohol intake predicts thromboembolism or death, even after adjustment for established clinical risk factors, and may help identify high risk AF patients who could be targeted for stroke and cardiovascular prevention strategies.
Source: Heart - July 5, 2013 Category: Cardiology Authors: Overvad, T. F., Rasmussen, L. H., Skjoth, F., Overvad, K., Albertsen, I. E., Lane, D. A., Lip, G. Y. H., Larsen, T. B. Tags: Editor's choice, Drugs: cardiovascular system, Epidemiology Heart rhythm disorders Source Type: research

Almanac 2013: Novel non-coronary cardiac interventions
Recent innovations in interventional cardiology have dramatically expanded the therapeutic options for patients with cardiac conditions. Interventional cardiology is no longer limited to the treatment of coronary artery disease but allows also treatment of valvular disease, stroke prevention, hypertension, etc. One of the most important new treatment options is the percutaneous treatment for aortic valve stenosis (transcatheter aortic valve implantation), since aortic valve disease is a rather common problem in elderly patients, with many of them at high risk for surgery. Similarly, mitral regurgitation is often associated...
Source: Heart - August 15, 2013 Category: Cardiology Authors: Meier, P., Franzen, O., Lansky, A. J. Tags: Drugs: cardiovascular system, Hypertension, Interventional cardiology, Aortic valve disease, Mitral valve disease Almanac 2013 Source Type: research

Secondhand smoke exposure and intermittent claudication: a Scotland-wide study of 4231 non-smokers
Conclusions As with coronary heart disease and stroke, SHS exposure was independently associated with IC. Our findings add to the published evidence in support of protecting the general public from SHS exposure.
Source: Heart - August 15, 2013 Category: Cardiology Authors: Lu, L., Mackay, D. F., Pell, J. P. Tags: Health policy, Drugs: cardiovascular system, Epidemiology, Tobacco use Peripheral vascular disease Source Type: research