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How to help patients make heart health changes: Q&A with Dr. Rakotz
Dietary and lifestyle changes are difficult to make. Once habits are formed, the effort that is required to change is often overwhelming for both patients and physicians. This week, Michael Rakotz, MD, director of chronic disease prevention with the AMA’s Improving Health Outcomes initiative, provides guidance from his own experience as a primary care physician on approaching heart healthy changes with patients. AMA Wire®: In our Twitter poll, the public thought 2:1 that exercise would benefit their heart health more than dietary changes. Why is that? Dr. Rakotz: It’s hard to know for sure why people voted this w...
Source: AMA Wire - September 29, 2015 Category: Journals (General) Authors: amamod Source Type: news

Using electronic health records to develop and validate a machine-learning tool to predict type 2 diabetes outcomes: a study protocol
Introduction Type 2 diabetes mellitus (T2DM) is a major cause of blindness, kidney failure, myocardial infarction, stroke and lower limb amputation. We are still unable, however, to accurately predict or identify which patients are at a higher risk of deterioration. Most risk stratification tools do not account for novel factors such as sociodemographic determinants, self-management ability or access to healthcare. Additionally, most tools are based in clinical trials, with limited external generalisability. Objective The aim of this work is to design and validate a machine learning-based tool to identify patients with T2...
Source: BMJ Open - July 30, 2021 Category: General Medicine Authors: Neves, A. L., Pereira Rodrigues, P., Mulla, A., Glampson, B., Willis, T., Darzi, A., Mayer, E. Tags: Open access, Health informatics Source Type: research

Variations and inter-relationship in outcome from emergency admissions in England: a retrospective analysis of Hospital Episode Statistics from 2005-2010
This study quantifies the scale of variation in three outcomes for a contemporary cohort of patients undergoing emergency medical and surgical admissions. The way in which the outcomes of different diagnoses relate to each other is investigated. Methods: A retrospective study using the English Hospital Episode Statistics 2005-2010 with one-year follow-up for all patients with one of 20 of the commonest and highest-risk emergency medical or surgical conditions. The primary outcome was in-hospital all-cause risk-standardised mortality rate (in-RSMR). Secondary outcomes were 1-year all-cause risk-standardised mortality rate (...
Source: BMC Health Services Research - June 19, 2014 Category: Journals (General) Authors: Peter HoltSidhartha SinhaBaris OzdemirAlan KarthikesalingamJan PolonieckiMatt Thompson Source Type: research

COGNITIVE-HD study: protocol of an observational study of neurocognitive functioning and association with clinical outcomes in adults with end-stage kidney disease treated with haemodialysis
Introduction The prevalence of cognitive impairment may be increased in adults with end-stage kidney disease compared with the general population. However, the specific patterns of cognitive impairment and association of cognitive dysfunction with activities of daily living and clinical outcomes (including withdrawal from treatment) among haemodialysis patients remain incompletely understood. The COGNITIVE impairment in adults with end-stage kidney disease treated with HemoDialysis (COGNITIVE-HD) study aims to characterise the age-adjusted and education-adjusted patterns of cognitive impairment (using comprehensive testing...
Source: BMJ Open - December 9, 2015 Category: Journals (General) Authors: Palmer, S. C., Ruospo, M., Barulli, M. R., Iurillo, A., Saglimbene, V., Natale, P., Gargano, L., Murgo, A. M., Loy, C., van Zwieten, A., Wong, G., Tortelli, R., Craig, J. C., Johnson, D. W., Tonelli, M., Hegbrant, J., Wollheim, C., Logroscino, G., Strippo Tags: Open access, Epidemiology, Neurology Protocol Source Type: research

AHA News: After Diabetes, Stroke and Heart Attack, She ' s Learning to ' Fight Smart '
THURSDAY, May 21, 2020 (American Heart Association News) -- Hyvelle Ferguson-Davis was reviewing paperwork at her office in Fort Lauderdale, Florida, when the headache started. It grew stronger and stronger and her eyes blurred, making it difficult...
Source: Drugs.com - Daily MedNews - May 21, 2020 Category: General Medicine Source Type: news

AlzEye: longitudinal record-level linkage of ophthalmic imaging and hospital admissions of 353 157 patients in London, UK
Purpose Retinal signatures of systemic disease (‘oculomics’) are increasingly being revealed through a combination of high-resolution ophthalmic imaging and sophisticated modelling strategies. Progress is currently limited not mainly by technical issues, but by the lack of large labelled datasets, a sine qua non for deep learning. Such data are derived from prospective epidemiological studies, in which retinal imaging is typically unimodal, cross-sectional, of modest number and relates to cohorts, which are not enriched with subpopulations of interest, such as those with systemic disease. We thus linked longitu...
Source: BMJ Open - March 16, 2022 Category: General Medicine Authors: Wagner, S. K., Hughes, F., Cortina-Borja, M., Pontikos, N., Struyven, R., Liu, X., Montgomery, H., Alexander, D. C., Topol, E., Petersen, S. E., Balaskas, K., Hindley, J., Petzold, A., Rahi, J. S., Denniston, A. K., Keane, P. A. Tags: Open access, Ophthalmology Source Type: research