Stroke RSS Page 8

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Source: Circulation
Condition: Atrial Fibrillation

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Total 235 results found since Jan 2013.

Consumer-Led Screening for Atrial Fibrillation: Frontier Review of the AF-SCREEN International Collaboration
Circulation. 2022 Nov 8;146(19):1461-1474. doi: 10.1161/CIRCULATIONAHA.121.058911. Epub 2022 Nov 7.ABSTRACTThe technological evolution and widespread availability of wearables and handheld ECG devices capable of screening for atrial fibrillation (AF), and their promotion directly to consumers, has focused attention of health care professionals and patient organizations on consumer-led AF screening. In this Frontiers review, members of the AF-SCREEN International Collaboration provide a critical appraisal of this rapidly evolving field to increase awareness of the complexities and uncertainties surrounding consumer-led AF s...
Source: Circulation - November 7, 2022 Category: Cardiology Authors: Axel Brandes Stavros Stavrakis Ben Freedman Sotiris Antoniou Giuseppe Boriani A John Camm Clara K Chow Eric Ding Johan Engdahl Michael M Gibson Gregory Golovchiner Taya Glotzer Yutao Guo Jeff S Healey Mellanie T Hills Linda Johnson Gregory Y H Lip Trudie Source Type: research

Comparative Effectiveness and Safety of Direct Oral Anticoagulants and Warfarin in Patients With Atrial Fibrillation and Chronic Liver Disease: A Nationwide Cohort Study
CONCLUSION: Among patients with AF and chronic liver disease, DOACs as a class were associated with lower risks of hospitalization for ischemic stroke/systemic embolism and major bleeding versus warfarin. However, the incidence of clinical outcomes among patients with AF and chronic liver disease varied between individual DOACs and warfarin, and in head-to-head DOAC comparisons.PMID:36762560 | DOI:10.1161/CIRCULATIONAHA.122.060687
Source: Circulation - February 10, 2023 Category: Cardiology Authors: Oluwadolapo D Lawal Herbert D Aronow Fisayomi Shobayo Anne L Hume Tracey H Taveira Kelly L Matson Yichi Zhang Xuerong Wen Source Type: research

Comparative Effectiveness of Left Atrial Appendage Occlusion Versus Oral Anticoagulation by Sex
CONCLUSIONS: In a real-world population of older Medicare beneficiaries with AF, compared with anticoagulation, LAAO was associated with a reduction in the risk of death, stroke, and long-term bleeding among women and men. These findings should be incorporated into shared decision-making with patients considering strategies for reduction in AF-related stroke.PMID:36780379 | DOI:10.1161/CIRCULATIONAHA.122.062765
Source: Circulation - February 13, 2023 Category: Cardiology Authors: Emily P Zeitler Stephen Kearing Megan Coylewright Devi Nair Jonathan C Hsu Douglas Darden A James O'Malley Andrea M Russo Sana M Al-Khatib Source Type: research

Flow-Gradient Patterns in Severe Aortic Stenosis with Preserved Ejection Fraction: Clinical Characteristics and Predictors of Survival.
CONCLUSIONS: NF/LG severe AS with preserved EF exhibits favorable survival with medical management and impact of AVR on survival was neutral. LF/LG severe AS is characterized by a high prevalence of atrial fibrillation, heart failure and reduced survival, and AVR was associated with improved survival. These findings have implications for evaluation of AS severity and subsequent management. PMID: 24048203 [PubMed - as supplied by publisher]
Source: Circulation - September 18, 2013 Category: Cardiology Authors: Eleid MF, Sorajja P, Michelena HI, Malouf JF, Scott CG, Pellikka PA Tags: Circulation Source Type: research

Outcomes of Temporary Interruption of Rivaroxaban Compared with Warfarin in Patients with Nonvalvular Atrial Fibrillation: Results from ROCKET AF.
CONCLUSIONS: TI of oral anticoagulation is common and associated with substantial stroke risks and bleeding risks that were similar among patients treated with rivaroxaban or warfarin. Further investigation is needed to determine the optimal management strategy in AF patients requiring TI of anticoagulation. CLINICAL TRIAL REGISTRATION INFORMATION: www.ClinicalTrials.gov. Identifier: NCT00403767. PMID: 24552831 [PubMed - as supplied by publisher]
Source: Circulation - February 19, 2014 Category: Cardiology Authors: Sherwood MW, Douketis JD, Patel MR, Piccini JP, Hellkamp AS, Lokhnygina Y, Spyropoulos AC, Hankey GJ, Singer DE, Nessel CC, Mahaffey KW, Fox KA, Califf RM, Becker RC, on behalf of the ROCKET AF Investigators Tags: Circulation Source Type: research

Comparing the Imperfect with the Imperfect: The Imprecise Science of Assessing the Risk and Benefits of Anticoagulation in Atrial Fibrillation.
Abstract Atrial Fibrillation (AF) is the most common arrhythmia in the United States, with approximately 7 million Americans estimated to have AF by 2020.(1,2) A major cause for morbidity and mortality in AF is stroke. Pharmacologic therapy for the prevention of stroke has undergone a renaissance with the advent of newer oral anticoagulants (NOACs) that are safe and effective alternatives to warfarin. However, the decision to initiate anticoagulation remains a subjective assessment of risks versus benefits. Although guided by well-validated risk scores for stroke and bleeding,(3,4,5) real world decisions on antico...
Source: Circulation - March 29, 2014 Category: Cardiology Authors: Ellenbogen KA, Tan AY Tags: Circulation Source Type: research

Does Myocardial Infarction Beget Atrial Fibrillation and Atrial Fibrillation Beget Myocardial Infarction?
Abstract Atrial fibrillation (AF) affects millions of people worldwide.(1) It is already known several decades that AF is not a benign condition, and it's associated with a 5-fold increased risk of stroke, 3-fold increased risk of heart failure, and doubling of risk of dementia and death.(2-4) Myocardial infarction, and coronary heart disease, are traditional risk factors of AF,(5) however, whether myocardial infarction is a consequence of AF, has not been studied in great detail yet. The focus of current treatment for AF is pointed towards prevention of stroke. This is of utmost importance; however the other card...
Source: Circulation - April 27, 2015 Category: Cardiology Authors: Vermond RA, Van Gelder IC, Crijns HJ, Rienstra M Tags: Circulation Source Type: research

Atrial Fibrillation and Ventricular Arrhythmias: Sex Differences in Electrophysiology, Epidemiology, Clinical Presentation, and Clinical Outcomes.
Abstract Sex-specific differences in the epidemiology, pathophysiology, clinical presentation, clinical treatment, and clinical outcomes of atrial fibrillation (AF), sustained ventricular arrhythmias, and sudden cardiac death are recognized. Sex hormones cause differences in cardiac electrophysiological parameters between men and women that may affect the risk for arrhythmias. The incidence and prevalence of AF is lower in women than in men. However, because women live longer and AF prevalence increases with age, the absolute number of women with AF exceeds that of men. Women with AF are more symptomatic, present ...
Source: Circulation - February 6, 2017 Category: Cardiology Authors: Gillis AM Tags: Circulation Source Type: research

Device-Related Thrombus After Left Atrial Appendage Closure: Incidence, Predictors, and Outcomes.
Conclusions -After LAAC with Watchman, DRT (~3.7%) is not frequent, but when present, is associated with a higher rate of stroke and systemic embolism. PMID: 29752398 [PubMed - as supplied by publisher]
Source: Circulation - May 11, 2018 Category: Cardiology Authors: Dukkipati SR, Kar S, Holmes DR, Doshi SK, Swarup V, Gibson DN, Maini B, Gordon NT, Main ML, Reddy VY Tags: Circulation Source Type: research

The Use of Biomarkers to Predict Specific Causes of Death in Patients with Atrial Fibrillation: Insights from the ARISTOTLE Trial.
Conclusions -Biomarkers were some of the strongest predictors of cause-specific death and may improve the ability to discriminate among patients' risks for different causes of death. These data suggest a potential role of biomarkers for identification of patients at risk for different causes of death in patients anticoagulated for AF. Clinical Trial Registration -URL: https://www.clinicaltrials.gov Unique Identifier: NCT00412984. PMID: 29871978 [PubMed - as supplied by publisher]
Source: Circulation - June 5, 2018 Category: Cardiology Authors: Sharma A, Hijazi Z, Andersson U, Al-Khatib SM, Lopes RD, Alexander JH, Held C, Hylek EM, Leonardi S, Hanna M, Ezekowitz JA, Siegbahn A, Granger CB, Wallentin L Tags: Circulation Source Type: research

Device-Detected Atrial Fibrillation: Evidencing the Knowledge Gap.
Abstract Stroke is a devastating complication of atrial fibrillation (AF) the odds of which can be reduced by use of oral anticoagulation based on the stroke risk score.1,2 Patients with asymptomatic clinical AF have a similar stroke risk as patients with symptomatic clinical AF.3 Thus far, electrocardiographic- (ECG) or Holter monitor-detected AF is a prerequisite before use of oral anticoagulation,1,2 because the guideline recommendations are based on studies that included only ECG- or Holter-detected AF ('clinical' AF).1,2 In the past decades increasing number of cardiac implantable electronic devices (CIED) ha...
Source: Circulation - March 16, 2019 Category: Cardiology Authors: Mulder BA, van Gelder IC, Rienstra M Tags: Circulation Source Type: research

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