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Source: Neurology
Condition: Pain

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Total 95 results found since Jan 2013.

Cervical artery dissection in patients >=60 years: Often painless, few mechanical triggers
Conclusion: In our study population of patients diagnosed with CeAD, 1 in 14 was aged ≥60 years. In these patients, pain and mechanical triggers might be missing, rendering the diagnosis more challenging and increasing the risk of missed CeAD diagnosis in older patients.
Source: Neurology - April 3, 2017 Category: Neurology Authors: Traenka, C., Dougoud, D., Simonetti, B. G., Metso, T. M., Debette, S., Pezzini, A., Kloss, M., Grond-Ginsbach, C., Majersik, J. J., Worrall, B. B., Leys, D., Baumgartner, R., Caso, V., Bejot, Y., Compter, A., Reiner, P., Thijs, V., Southerland, A. M., Ber Tags: Stroke in young adults, All Cerebrovascular disease/Stroke, Carotid artery dissection ARTICLE Source Type: research

Teaching NeuroImages: Acute isolated oculomotor nerve palsy of microvascular origin
A 73-year-old man presented with acute-onset, right-sided ptosis and pain above the right eye. His medical history noted hypertension and diabetes. On physical examination, an isolated right oculomotor palsy was noted with preserved pupillary function. An MRI scan revealed isolated swelling of superior, inferior, and medial rectus muscle at the right side (figure). No cause other than presumed microvascular oculomotor nerve ischemia was shown.1 In patients aged 50 years or older, isolated ocular motor nerve palsies are most likely due to microvascular ischemia, but other etiologies such as aneurysm, brainstem stroke, and m...
Source: Neurology - August 14, 2016 Category: Neurology Authors: van den Wijngaard, I. R., Hagenbeek, R. E., Jellema, K., Lycklama a Nijeholt, G. J. Tags: MRI, Other cerebrovascular disease/ Stroke, All Clinical Neurology, Ocular motility RESIDENT AND FELLOW SECTION Source Type: research

Stroke like migraine attacks after radiation therapy (SMART) syndrome a case series of three patients (P6.179)
Conclusions:Our patients represent the first case series of SMART syndrome in a single institution. Our cases share similarities to the prior reports in the literature and highlights the clinical and MRI triad of acute onset headaches, neurological deficits and MRI findings of transient contrast enhancement of the cortex with white matter sparing in a previous radiation field.Disclosure: Dr. rauf has nothing to disclose. Dr. Boulter has nothing to disclose. Dr. Imitola has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Rauf, Y., Boulter, D., Imitola, J. Tags: Neurologic Complications of Cancer Source Type: research

The Effect of SSRIs in the Outcomes of ICARE Trial (P4.040)
Conclusions:Despite having similar baseline scores as non-SSRI users, SSRI users had 12-month PHQ-9 scores suggestive of mild depression while non-SSRI users did not. There was no imbalance in SSRI use for the 3 treatment arms, ruling out an effect on overall motor outcomes. SSRIs affected outcomes in the different trial arms in different ways which supports the hypothesis that medications can affect rehabilitation interventions.Study Supported by: National Institute of Neurological Disorders and Stroke, and the National Center for Medical Rehabilitation Research (U01 NS056256)Disclosure: Dr. Belagaje has nothing to disclo...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Belagaje, S., Blanton, S., Ding, L., Lane, C., Nelsen, M., Dromerick, A., Winstein, C., Wolf, S. Tags: Neuro-rehabilitation: Motor Recovery and Spasticity Treatment Source Type: research

Do patients with thalamic pain have a specific somatosensory phenotype? (P1.222)
Conclusions:The somatosensory phenotype of the CPSP patients was characterized by reduced sensation for vibration and light touch on the affected side. These patients showed mechanical hyperalgesia and more pronounced hypoesthesia, but no temperature perception abnormalities, compared to the control patients. Our results do not support the view that a specific dysfunction of the spinothalamic tract is involved in the pathogenesis of thalamic CPSP.Disclosure: Dr. Papadopoulou has nothing to disclose. Dr. Magon has nothing to disclose. Dr. Gaetano has received personal compensation for activities with Novartis Pharmaceutical...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Papadopoulou, A., Magon, S., Gaetano, L., Jaeger, Y., Kappos, L., Sprenger, T. Tags: Pain and Palliative Care Source Type: research

Lasting Relief from Chronic Pain after Cerebral Infarction (P02.005)
CONCLUSIONS: This patient's stroke appeared to produce the beneficial and persistent effect of dramatic pain relief, enabling him to discontinue all analgesic medications, including methadone. The alleviation of pain after ischemic infarction is highly unusual, and possible explanations include 1) damage to both anterior cingulate gyri producing apathy of such severity that the experience of pain was markedly blunted, and 2) bilateral injury to the nucleus accumbens abolishing a cerebral region critical for the appreciation of pain and opiate-related reward.Disclosure: Dr. Burke has nothing to disclose. Dr. Anderson's spou...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Burke, H., Anderson, C., Filley, C. Tags: P02 Ethics, Pain, and Palliative Care Source Type: research

Intracranial Arterial Dissection (P2.013)
CONCLUSIONS:IAD represent a substantial proportion of CAD and may be a frequently underdiagnosed cause of stroke. Intraparenchymal hemorrhage seemed to occur less frequently in our series than previously reported.Study Supported by:Disclosure: Dr. Dossi has nothing to disclose. Dr. Farez has received personal compensation for activities with Merck Serono. Dr. Farez has received research support from Novartis. Dr. Arena has nothing to disclose. Dr. Pujol Lereis has nothing to disclose. Dr. Povedano has nothing to disclose. Dr. Ameriso has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Dossi, D., Farez, M., Arena, J., Pujol Lereis, V., Povedano, G., Ameriso, S. Tags: Cerebrovascular Disease and Interventional Neurology I Source Type: research

A Case of Resolution of Thalamic Pain Syndrome Following Endovascular Stenting (P4.352)
Conclusions: CPSP may be in part due to chronic hypoperfusion. Endovascular stenting may have led to the resolution of the patient’s CPSP.Disclosure: Dr. Le has nothing to disclose. Dr. Rasmussen has nothing to disclose. Dr. Noonan has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Le, S., Rasmussen, J., Noonan, P. Tags: Cerebrovascular Case Reports Source Type: research

Toward an epidemiology of poststroke spasticity
Poststroke spasticity (PSS)-related disability is emerging as a significant health issue for stroke survivors. There is a need for predictors and early identification of PSS in order to minimize complications and maladaptation from spasticity. Reviewing the literature on stroke and upper motor neuron syndrome, spasticity, contracture, and increased muscle tone measured with the Modified Ashworth Scale and the Tone Assessment Scale provided data on the dynamic time course of PSS. Prevalence estimates of PSS were highly variable, ranging from 4% to 42.6%, with the prevalence of disabling spasticity ranging from 2% to 13%. Da...
Source: Neurology - January 14, 2013 Category: Neurology Authors: Wissel, J., Manack, A., Brainin, M. Tags: ARTICLE Source Type: research

Use of Veterans Specific Activity Questionnaire VSAQ to Estimate Exercise Tolerance in Ambulatory Amyotrophic Lateral Sclerosis (ambALS) Patients (P2.071)
CONCLUSIONS:VSAQ is a practical tool to estimate exercise capacity of ambALS and may be used for safe exercise prescription.Disclosure: Dr. Sanjak has nothing to disclose. Dr. Headen has nothing to disclose. Dr. Barrett has nothing to disclose. Dr. Holsten has nothing to disclose. Dr. Langford has nothing to disclose. Dr. Bravver has received research support from Biogen Idec, Avanier, Cytokinetics Pharmaceuticals, Neuraltus Pharmaceuticals, GlaxoSmithKline Inc., the National Institute of Neurological Disorders and Stroke, and the Clinical Research Consortium. Dr. Bockenek has nothing to disclose. Dr. Desai has received pe...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Sanjak, M., Headen, J., Barrett, K., Holsten, S., Langford, V., Bravver, E., Bockenek, W., Desai, U., Story, J. S., Lindblom, S. C., Paccico, T., Brooks, B. Tags: ALS: Genetics and Outcomes Source Type: research

Patient Registry of Outcomes in Spasticity (PROS) Care World (P3.050)
Conclusion: Findings suggest dosing differences for commonly treated patterns of UMN dysfunction and improved Ashworth and pain scores. This robust database can guide clinicians in the management of patients with spasticity.Disclosure: Dr. Esquenazi has nothing to disclose. Dr. Mayer has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Esquenazi, A., Mayer, N., Lee, S. Tags: Neural Repair and Neuro-rehabilitation: Clinical Source Type: research

Restless Limbs Syndrome (RLS) Presenting as Hemisyndrome: A Case of Dejerine-Roussy Syndrome Responsive to Dopamine Agonists (P5.266)
CONCLUSION: Recognition of RLS as a hemisyndrome may offer new treatments for patients with chronic dysesthetic pain, paresthesia, and insomnia as illustrated in this case of DRS. RLS affects 10% of the population and DRS is seen in 10% after thalamic stroke. Pain associated with RLS may be contributing to chronic, persistent pain in patients with certain CNS lesions and may be treatable with Dopamine Agonists.Disclosure: Dr. Dickoff has received personal compensation for activities with UCB Pharma and Teva pharmaceuticals as a speaker.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Dickoff, D. Tags: Movement Disorders: Sleep and Movement Disorders and Miscellaneous Diagnoses Source Type: research

Internal Carotid Artery Stenosis and Flow Diversion: Relationship with Headache (P6.099)
Conclusion: Recognition of flow-diversion into the ECA as a possible mechanism for headaches may help in further understanding of ICA disease, its progression, and effects of carotid revascularization on quality of life. Headache as a likely surrogate marker of carotid stenosis with flow-diversion warrants more research, and may be critical in the early identification of significant ICA stenosis and prevention of TIA or stroke.Disclosure: Dr. Herial has nothing to disclose. Dr. Miran has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Herial, N., Miran, M. S., Saleem, M., Qureshi, I., Qureshi, A. Tags: Headache: Clinical Presentation/Diagnosis Source Type: research

Poststroke spasticity: Treating to the disability
People who have strokes are subject to numerous potentially devastating sequelae, most often sensorimotor paresis, impairment of cognition and language, and other functional disabilities, including depression and dementia. Of these sequelae, spasticity occurring with motor dysfunction is a frequent finding that has to be evaluated in light of other diagnoses, such as central paresis, ataxia, pathologic stance or gait, and other coordination dysfunctions. Often, spasticity is not notably present in acute ischemic strokes but develops later on, and may then become a major obstacle for achieving independence in performance of...
Source: Neurology - January 14, 2013 Category: Neurology Authors: Brainin, M. Tags: INTRODUCTION Source Type: research

The History of Aspirin: from Willow Bark to Thomas Edison in the 20th Century (P2.391)
CONCLUSION: The evolution of Aspirin in the 20th century aligned with historical events leading to its place as one of the most widely used drugs in history.Disclosure: Dr. Southerland has received personal compensation in an editorial capacity for Neurology podcast.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Southerland, A. Tags: History of Neurology Source Type: research