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Acute ischemic stroke management: concepts and controversies.A narrative review
Expert Rev Neurother. 2021 Jan;21(1):65-79. doi: 10.1080/14737175.2021.1836963. Epub 2020 Nov 2.ABSTRACTINTRODUCTION: Amongst the 25.7 million survivors and 6.5 million deaths from stroke between 1990 and 2013, ischemic strokes accounted for approximately 70% and 50% of the cases, respectively. With patients still suffering from complications and stroke recurrence, more questions have been raised as to how we can better improve patient management.AREAS COVERED: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and Newcastle-Ottawa Scale (NOS) were adopted to ensure a comprehensive in...
Source: Expert Review of Neurotherapeutics - October 13, 2020 Category: Neurology Authors: Ka Hou Christien Li Aaron Jesuthasan Christopher Kui Ruth Davies Gary Tse Gregory Y H Lip Source Type: research

Anti-hypertensive agents in Alzheimer's disease: beyond vascular protection.
Authors: Lebouvier T, Chen Y, Duriez P, Pasquier F, Bordet R Abstract INTRODUCTIONMidlife hypertension has been consistently linked with increased risk of cognitive decline and Alzheimer's disease (AD). Observational studies and randomized trials show that the use of antihypertensive therapy is associated with a lesser incidence or prevalence of cognitive impairment and dementia. However, whether anti-hypertensive agents specifically target the pathological process of AD remains elusive.AREAS COVEREDThis review of literature provides an update on the clinical and preclinical arguments supporting anti-AD properties of ...
Source: Expert Review of Neurotherapeutics - December 24, 2019 Category: Neurology Tags: Expert Rev Neurother Source Type: research

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