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Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies
CONCLUSIONS: Inverse non-linear dose-response associations suggest substantial protection against a range of chronic disease outcomes from small increases in non-occupational physical activity in inactive adults. PROSPERO registration number CRD42018095481.PMID:36854652 | DOI:10.1136/bjsports-2022-105669
Source: British Journal of Sports Medicine - February 28, 2023 Category: Sports Medicine Authors: Leandro Garcia Matthew Pearce Ali Abbas Alexander Mok Tessa Strain Sara Ali Alessio Crippa Paddy C Dempsey Rajna Golubic Paul Kelly Yvonne Laird Eoin McNamara Samuel Moore Thiago Herick de Sa Andrea D Smith Katrien Wijndaele James Woodcock Soren Brage Source Type: research

Clonal Hematopoiesis of Indeterminate Potential: Current Understanding and Future Directions
This article summarizes the current knowledge about clonal hematopoiesis of indeterminate potential (CHIP), its association with cardiovascular disease (CVD), and other outcomes, pathogenesis, postulated mechanisms of various pathologies, current knowledge gaps, possible targets of intervention, and therapeutic implications.Recent FindingsRecently, a common age-related hematological entity known as CHIP has been identified as the independent risk factor for CVD. CHIP is defined as the presence of clonally expanded blood cells involving leukemogenic mutations without the evidence of malignancy. CHIP is known to increase the...
Source: Current Oncology Reports - March 16, 2023 Category: Cancer & Oncology Source Type: research

Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies
Conclusions Inverse non-linear dose–response associations suggest substantial protection against a range of chronic disease outcomes from small increases in non-occupational physical activity in inactive adults. PROSPERO registration number CRD42018095481.
Source: British Journal of Sports Medicine - July 20, 2023 Category: Sports Medicine Authors: Garcia, L., Pearce, M., Abbas, A., Mok, A., Strain, T., Ali, S., Crippa, A., Dempsey, P. C., Golubic, R., Kelly, P., Laird, Y., McNamara, E., Moore, S., de Sa, T. H., Smith, A. D., Wijndaele, K., Woodcock, J., Brage, S. Tags: Open access, BJSM Reviews with MCQs, BJSM Systematic review Source Type: research

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