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Direct saturation-corrected chemical exchange saturation transfer MRI of glioma: Simplified decoupling of amide proton transfer and nuclear overhauser effect contrasts.
CONCLUSION: The proposed DISC-CEST method, by correction of nonlinear direct water saturation effect, serves as a promising alternative to both the commonly used MTRasym and the simplistic three-offset analyses. It provides simple yet reliable in vivo CEST quantification such as APT and NOE mapping in brain tumor, which is promising for clinical translation. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine. PMID: 29030880 [PubMed - as supplied by publisher]
Source: Magnetic Resonance in Medicine - October 13, 2017 Category: Radiology Authors: Yuwen Zhou I, Wang E, Cheung JS, Lu D, Ji Y, Zhang X, Fulci G, Sun PZ Tags: Magn Reson Med Source Type: research

< mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" > < mml:mrow > < mml:msubsup > < mml:mi > T < /mml:mi > < mml:mn > 2 < /mml:mn > < mml:mo > ' < /mml:mo > < /mml:msubsup > < /mml:mrow > < /mml:math > mapping of the brain from water-unsuppressed < sup > 1 < /sup > H-MRSI  and turbo spin-echo data
CONCLUSIONS: High-quality T 2 ' $$ {\mathrm{T}}_2^{\prime } $$ maps can be obtained from water-unsuppressed 1 H-MRSI and TSE data using the proposed method. With further development, this method may lay a foundation for simultaneously imaging oxygenation and neurometabolic alterations of brain disorders.PMID:35844075 | DOI:10.1002/mrm.29386
Source: Magnetic Resonance in Medicine - July 18, 2022 Category: Radiology Authors: Tianxiao Zhang Rong Guo Yudu Li Yibo Zhao Yao Li Zhi-Pei Liang Source Type: research