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Specialty: Drugs & Pharmacology
Source: European Journal of Pharmacology
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Total 1 results found since Jan 2013.
Lauric acid provides neuroprotection against oxidative stress in mouse model of hyperglycaemic stroke
Eur J Pharmacol. 2023 Aug 10:175990. doi: 10.1016/j.ejphar.2023.175990. Online ahead of print.ABSTRACTDuring ischemic stroke, higher glucose level linked worse outcomes were reported even in patients without pre-existing diabetes. Evidence suggest that such worse stroke outcomes were mainly due to production of reactive, toxic glucose metabolites that expands oxidative damage inside the brain. As a consequence of high oxidative stress, microvasculature structures and tight junctions compromised their functionally, infarct volume expands and brain edema exacerbates. In a mouse model of ischemic stroke with induced acute hyp...
Source: European Journal of Pharmacology - August 12, 2023 Category: Drugs & Pharmacology Authors: Zaib Ali Shaheryar Mahtab Ahmad Khan Huma Hameed Syed Awais Ali Zaidi Irfan Anjum Muhammad Shafeeq Ur Rahman Source Type: research
