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Low-dose aspirin and risk of intracranial bleeds: An observational study in UK general practice
Conclusion: Low-dose aspirin is not associated with an increased risk of any type of ICB and is associated with a significantly decreased risk of SAH when used for ≥1 year.
Source: Neurology - November 27, 2017 Category: Neurology Authors: Cea Soriano, L., Gaist, D., Soriano-Gabarro, M., Bromley, S., Garcia Rodriguez, L. A. Tags: All Cerebrovascular disease/Stroke, Case control studies, Risk factors in epidemiology ARTICLE Source Type: research

Can CREST Procedural Results Be Reproduced in General Practice in Post CREST Era? Analysis of National Surgical Quality Improvement Program (NSQIP) Registry (S42.001)
Conclusions: Our results support reproducibility of CREST procedural outcomes for both CEA and CAS in general practice in post-trial period.Disclosure: Dr. Jani has nothing to disclose. Dr. Zafar has nothing to disclose. Dr. Afzal has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Jani, V., Zafar, A., Afzal, M., Qureshi, A. Tags: Stroke Mechanism and Modifiers Source Type: research

Oxidative phosphorylation and lacunar stroke: Genome-wide enrichment analysis of common variants
Conclusions: Our results implicate the OXPHOS pathway in the pathogenesis of lacunar stroke, and show the association is specific to patients with the MLI/LA subtype. They show that MRI-based subtyping of lacunar stroke can provide insights into disease pathophysiology, and imply that different radiologic subtypes of lacunar stroke subtypes have distinct underlying pathophysiologic processes.
Source: Neurology - January 11, 2016 Category: Neurology Authors: Traylor, M., Anderson, C. D., Hurford, R., Bevan, S., Markus, H. S. Tags: MRI, All Cerebrovascular disease/Stroke, Case control studies, Association studies in genetics ARTICLE Source Type: research

Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK
Conclusion: HZ is an independent risk factor for vascular disease in the UK population, particularly for stroke, TIA, and MI in subjects affected before the age of 40 years. In older subjects, better ascertainment of vascular risk factors and earlier intervention may explain the reduction in risk of stroke after HZ infection.
Source: Neurology - July 7, 2014 Category: Neurology Authors: Breuer, J., Pacou, M., Gautier, A., Brown, M. M. Tags: CORRECTED AND REPUBLISHED ARTICLES Source Type: research

Risk of incident stroke in patients with Alzheimer disease or vascular dementia
Conclusions: Patients with VD, but not AD, have a markedly higher risk of developing an ischemic stroke than those without dementia. In patients with AD, but not VD, use of atypical antipsychotic drugs was associated with an increased risk of TIA.
Source: Neurology - September 2, 2013 Category: Neurology Authors: Imfeld, P., Bodmer, M., Schuerch, M., Jick, S. S., Meier, C. R. Tags: All Cerebrovascular disease/Stroke, Alzheimer's disease, Vascular dementia, Case control studies, Incidence studies ARTICLE Source Type: research