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Source: Journal of NeuroInterventional Surgery
Therapy: Thrombolytic Therapy

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Total 15 results found since Jan 2013.

E-108 Endovascular treatment of patients with acute ischemic stroke due to underlying arterial dissection: a nationwide analysis
ConclusionsDespite a similar prevalence among patients admitted for AIS, CA dissections are associated with a higher rate of endovascular intervention and poorer short-term outcomes compared to VA dissections. This study provides essential epidemiologic and outcome data for the cerebrovascular neurosurgeon.Abstract E-108 Table 1Comparison of clinical characteristics and outcomes among patients presenting with acute ischemic stroke due to carotid or vertebral artery dissections Characteristic Vertebral Artery Dissection, N = 2,562 Carotid Artery Dissection, N = 2,789 p-value1 Age (years), Mean (SD) 53 (17) 57 (17) <0.00...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brandel, M., McCann, C., Wali, A., Wu, V., Esmail, S., Steinberg, J., Olson, S., Pannell, J., Khalessi, A., Santiago-Dieppa, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-125 Clinical outcomes of mechanical thrombectomy in posterior circulation tandem occlusions: multicenter experience
ConclusionMechanical thrombectomy for posterior circulation tandem occlusions is feasible with reasonable clinical outcomes, despite a high rate of rescue stenting.Disclosures M. Salem: None. G. Sioutas: None. M. Mohammaden: None. A. Luisa Kuhn: None. A. Luisa Kuhn: None. A. Luisa Kuhn: None. C. Tschoe: None. M. Tarek: None. A. Dmytriw: None. R. Regenhardt: None. S. Marioni: None. M. AbdalKader: None. G. Cortez: None. V. Srinivasan: None. T. Nguyen: None. S. Tjoumakaris: None. A. Puri: None. V. Pereira: None. J. Rabinov: None. J. Seigler: None. R. Hanel: None. S. Sheth: None. A. Siddiqui: None. E. Levy: None. D. Haussen: N...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Salem, M., Sioutas, G., Mohammaden, M., Luisa Kuhn, A., Luisa Kuhn, A., Luisa Kuhn, A., Tschoe, C., Tarek, M., Dmytriw, A., Regenhardt, R., Marioni, S., AbdalKader, M., Cortez, G., Srinivasan, V., Nguyen, T., Tjoumakaris, S., Puri, A., Pereira, V., Rabino Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-048 Antithrombotics for emergent stenting in acute stroke
ConclusionTirofiban continuous infusion is a safe and possibly effective strategy for emergent stenting in acute ischemic stroke.Disclosures S. Lahoti: None. K. Limaye: None. C. Zevallos: None. K. Dlouhy: None. M. Hayakawa: None. E. Samaniego: None. D. Hasan: None. S. Ortega: 2; C; Medtronic, Stryker Neurovascular, Microvention. C. Derdeyn: 1; C; Siemens Healthineers. 4; C; Euphrates Vascular, Inc. 6; C; DSMB: Penumbra (MIND), NoNO (ESCAPE NA1 and FRONTIER).
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Lahoti, S., Limaye, K., Zevallos, C., Dlouhy, K., Hayakawa, M., Samaniego, E., Hasan, D., Ortega, S., Derdeyn, C. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

EP63 The TAPAS study: thrombectomy aspiration post-market study in acute stroke
ConclusionThe Q Catheter showed good deliverability and revascularization rates in this real-world setting with no safety concerns.ReferenceLong TD, Kallmes DF, Hanel R, Shigematsu T, Halaszyn AM, Wolter J, Berenstein A. Novel aspiration catheter design for acute stroke thrombectomy. J Neurointerv Surg 2019 Feb;11(2):190–195.DisclosureConsultant MIVI Neuroscience, Inc.
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Ballenilla Marco, F., Espinosa, M., Zamarro, J., Masso, J., Garmendia, E., Pumar, J., Larrea, J., Mosqueira, A. Tags: Treatment Source Type: research

O-019 Increasing inner diameter leads to faster thrombectomy with aspiration in acute ischemic stroke
ConclusionThis multicenter, consecutive real-world experience demonstrates that M1 thrombectomy with a larger distal ID catheter is associated with faster time to recanalization and higher rate of TICI 2C or better recanalization on first pass, but also with a higher rate of hemorrhage on follow up imaging.Disclosures J. Vargas: 2; C; Cerenovus. 4; C; Truvic. S. Majidi: None. G. Cortez: None. A. Aghaebrahmin: None. E. Sauvageau: None. R. Hanel: 1; C; Microvention, Stryker. 2; C; Stryker, Medtronic, Cerenovus, Balt, Q’APel. 4; C; Rist. 6; C; MiVI. H. Hawk: None. S. Nimjee: None. A. Zakeri: None. M. Mokin: 2; C; Medtro...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Vargas, J., Majidi, S., Cortez, G., Aghaebrahmin, A., Sauvageau, E., Hanel, R., Hawk, H., Nimjee, S., Zakeri, A., Mokin, M., Chen, C., Kellogg, R., Turk, A., Deleacy, R., Siddiqui, A., Oselkin, M., Marlin, E., TUrner, R., Chaudry, I., Milburn, J. Tags: Oral abstracts Source Type: research

P-007 Safety and efficacy of endovascular thrombectomy for distal vessel occlusion (DLV): single center experience
ConclusionThis single center, consecutive real-world experience demonstrates that thrombectomy in DVO stroke patients is safe and leads to high rate of successful recanalization. Further studies are warranted to evaluate the efficacy of thrombectomy in DVO in comparison to best medical management.Disclosures S. Majidi: None. S. Matsoukas: None. R. De Leacy: None. T. Oxley: None. H. Shoirah: None. T. Shigematsu: None. C. Kellner: None. J. Fifi: None. J. Mocco: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Majidi, S., Matsoukas, S., De Leacy, R., Oxley, T., Shoirah, H., Shigematsu, T., Kellner, C., Fifi, J., Mocco, J. Tags: Oral poster abstracts Source Type: research

P-009 An angled tip is associated with improved technical outcomes when using 0.064-0.074 aspiration catheters: analysis from a multicenter retrospective cohort
ConclusionThis multicenter, consecutive real-world experience demonstrates that M1 thrombectomy with an angled tip aspiration catheter is associated with higher rates of TICI 2C or better reperfusion, equal rates of TICI 2B or better reperfusion, and faster time to successful reperfusion.Disclosures J. Vargas: None. S. Majidi: None. H. Hawk: None. S. Nimjee: None. A. Zakeri: None. M. Mokin: None. R. Kellogg: None. G. Cortez: None. A. Aghaebrahim: None. E. Sauvageau: None. R. Hanel: None. R. De Leacy: None. A. Siddiqui: None. A. Turk: None. M. Oselkin: None. E. Marlin: None. R. Turner: None. I. Chaudry: None. J. Milburn: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Vargas, J., Majidi, S., Hawk, H., Nimjee, S., Zakeri, A., Mokin, M., Kellogg, R., Cortez, G., Aghaebrahim, A., Sauvageau, E., Hanel, R., De Leacy, R., Siddiqui, A., Turk, A., Oselkin, M., Marlin, E., Turner, R., Chaudry, I., Milburn, J. Tags: Oral poster abstracts Source Type: research

P-012 Thrombectomy aspiration post-market study in acute stroke: the TAPAS study
ConclusionThe Q Aspiration Catheter is a novel technology that showed comparable deliverability and revascularization rates as other commercially available catheters with no safety concerns. More prospective clinical data is needed to fully assess the Q Aspiration Catheter.AbbreviationsAIS (acute ischemic stroke), MT (mechanical thrombectomy), ASPECTs (Alberta Stroke Program Early CT Score), mTICI (modified TICI score), NIHSS (National Institute of Health Stroke Scale), mRS (modified Rankin Scale), ENT (embolization to a new territory), sICH (symptomatic intracranial hemorrhage)Disclosures F. Ballenilla: 2; C; MIVI Neurosc...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Ballenilla, F., Espinosa, M., Zamarro, J., Masso, J., Garmendia, E., Pumar, J., Larrea, J., Mosqueira, A. Tags: Oral poster abstracts Source Type: research

P-015 The zoom system demonstrates higher first pass effect and faster reperfusion as compared to a consecutive contemporaneous series of aspiration catheters: analysis from a multicenter retrospective cohort
ConclusionThis retrospective, multicenter, consecutive real-world experience suggests that using Zoom 088 or 071 as primary aspiration catheter may demonstrate superior technical outcomes for M1 thrombectomy.Disclosures S. Majidi: None. J. Vargas: 2; C; Cerenovus, Medtronic. 4; C; Truvic. H. Hawk: None. S. Nimjee: None. A. Zakeri: None. M. Mokin: 2; C; Medtronic, Cerenovus. R. Kellogg: None. R. DeLeacy: None. G. Cortez: None. A. Aghaebrahmin: None. E. Sauvageau: None. R. Hanel: 1; C; Microvention, Stryker. 2; C; Medtronic, Microvention, Stryker, Balt, Cerenovus, Q’Apel. A. Siddiqui: 2; C; Imperitive Care, Medtronic, ...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Majidi, S., Vargas, J., Hawk, H., Nimjee, S., Zakeri, A., Mokin, M., Kellogg, R., DeLeacy, R., Cortez, G., Aghaebrahmin, A., Sauvageau, E., Hanel, R., Siddiqui, A., Oselkin, M., Marlin, E., Turk, A., Turner, R., Chaudry, I., Milburn, J. Tags: Oral poster abstracts Source Type: research

E-045 Early neurological improvement is independent predictor of favorable outcome following thrombectomy for basilar artery occlusion
ConclusionENI is an independent predictor of favorable clinical outcome after BAO thrombectomy. Single pass successful recanalization is associated with higher likelihood of ENI.Disclosures S. Majidi: 1; C; SNIS Foundation. S. Matsoukas: None. R. De Leacy: None. T. Oxley: None. H. Shoirah: None. T. Shigematsu: None. C. Kellner: None. J. Mocco: None. J. Fifi: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Majidi, S., Matsoukas, S., De Leacy, R., Oxley, T., Shoirah, H., Shigematsu, T., Kellner, C., Mocco, J., Fifi, J. Tags: Electronic poster abstracts Source Type: research

Endovascular mechanical thrombectomy for cerebral venous sinus thrombosis: a systematic review
Conclusions EMT is an effective salvage therapy for refractory CVST, with a reasonable safety profile. Chemical thrombolysis, in conjunction with EMT, did not appear to result in additional harm or benefit. Further analysis is warranted to determine predictors of success after EMT for CVST.
Source: Journal of NeuroInterventional Surgery - October 13, 2017 Category: Neurosurgery Authors: Ilyas, A., Chen, C.-J., Raper, D. M., Ding, D., Buell, T., Mastorakos, P., Liu, K. C. Tags: Ischemic stroke Source Type: research

'Last known well alone should not determine triage for patients with stroke and symptoms of large vessel occlusion
The term ‘last known well’ (LKW) is ingrained in the culture of stroke treatment. There are good reasons for this. Successful acute thrombolytic trials used LKW as an entry criterion to prove the efficacy of IV thrombolysis.1 2 Based on the results of those trials, treatment of acute stroke with IV thrombolysis is a class 1 recommendation for patients presenting with acute stroke symptoms within 3–4.5 h of LKW.3 Few vascular neurologists will recommend IV thrombolysis for patients outside the time window established by LKW, and hence this term represents a crucial time metric for thrombolytic therapy...
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Heck, D. V., Grotta, J. C. Tags: Editorials Source Type: research

Different risk factors for poor outcome between patients with positive and negative susceptibility vessel sign
Conclusions The risk factors for clinical outcome after IVT in patients with negative SVS may differ from those with positive SVS.
Source: Journal of NeuroInterventional Surgery - September 12, 2016 Category: Neurosurgery Authors: Yan, S., Liu, K., Tong, L., Yu, Y., Zhang, S., Lou, M. Tags: Ischemic stroke Source Type: research

Acute ischemic stroke in a child due to basilar artery occlusion treated successfully with a stent retriever
We present the case of a 22-month-old child with acute ischemic stroke due to basilar artery occlusion that was successfully treated with a stent retriever.
Source: Journal of NeuroInterventional Surgery - July 13, 2016 Category: Neurosurgery Authors: Savastano, L., Gemmete, J. J., Pandey, A. S., Roark, C., Chaudhary, N. Tags: Electronic pages Source Type: research

Multicenter clinical experience in over 125 patients with the Penumbra Separator 3D for mechanical thrombectomy in acute ischemic stroke
Conclusions The results suggest that the Separator 3D enables safe and effective revascularization of occluded large arteries in acute stroke intervention, leading to a high rate of functional independence at 90 days.
Source: Journal of NeuroInterventional Surgery - December 13, 2015 Category: Neurosurgery Authors: Behme, D., Kowoll, A., Mpotsaris, A., Hader, C., Hechelhammer, L., Weber, J., Weber, W. Tags: Ischemic stroke Source Type: research