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E-021 Pathophysiology, stroke types, collateral formation and aneurysms in moyamoya disease/moya moya syndrome
ConclusionsMMD is presented most commonly with ischemic stroke in the pediatric age group and with hemorrhagic stroke in the adult age group. MMD-associated intracranial aneurysms frequently occur in patients presenting with hemorrhagic unilateral MMD and are associated with an extremely high rate of rupture. Long-standing hemodynamic stress might contribute to the formation of an aneurysm.Disclosures S. Ahmad: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Ahmad, S. Tags: Electronic poster abstracts Source Type: research

The mission lifeline severity-based stroke treatment algorithm: We need more time
On March 10th, 2017 the American Heart Association presented their Mission Lifeline Severity-Based Stroke Treatment Algorithm For EMS. This document consisted of single page algorithm written to provide guidance to EMS providers regarding the triage and transport of suspected stroke patients, as well as a single explanatory page (https://www.heart.org/HEARTORG/Professional/MissionLifelineHomePage/MissionLifeline-Stroke_UCM_491623_SubHomePage.jsp). Specifically, patients with suspected emergent large vessel occlusion (ELVO) (based on pre-hospital stroke assessment), who were last know well within 6 hours, are to be consider...
Source: Journal of NeuroInterventional Surgery - April 13, 2017 Category: Neurosurgery Authors: Mocco, J., Fiorella, D., Albuquerque, F. C. Tags: Editors ' column Source Type: research

P-031 Effect of COVID-19 on acute ischemic stroke: population-level experience
ConclusionIn this population-level study, significant decreases in AIS volume were observed with slightly higher incidence in younger population and higher LVO strokes. Rates of thrombolysis and thrombectomy remained unchanged but patients appeared to have worse outcomes.Disclosures Y. Kim: None. S. Khose: None. S. Salazar-Marioni: None. R. Abdelkhaleq: None. S. Sheth: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Kim, Y., Khose, S., Salazar-Marioni, S., Abdelkhaleq, R., Sheth, S. Tags: Oral poster abstracts Source Type: research

Getting ahead of stroke
In 2015, multiple randomized controlled trials clearly demonstrated that mechanical thrombectomy could save lives and prevent disability in patients with large vessel acute ischemic stroke. Neurointerventional surgeons and stroke neurologists celebrated a great win for our patients. We soon realized, however, that the hard work of implementation lay ahead. Hospitals and emergency medical services (EMS) were not optimally designed to ensure that patients with a stroke were brought to the right hospital rather than the closest one. These shortcomings resulted in patients unnecessarily being transferred between hospitals to r...
Source: Journal of NeuroInterventional Surgery - July 14, 2022 Category: Neurosurgery Authors: Mack, W. J. Tags: Editor ' s column Source Type: research

O-007 german thrombectomy database from 2012 to 2014: experiences from 9,365 acute stroke interventions
DiscussionRecanalization rates, functional outcomes and the rate of intraprocedural hemorrhages are in line with the data of the recently published RCTs. The absolute numbers need to be considered with caution as self-reported rates are usually more optimistic than evaluations by independent adjudicators. During the observation period there were no clear trends towards better outcomes or decreasing rates of rare complications. The data of the German DGNR/DeGIR-database suggest that thrombectomy is generally conducted in German stroke centers with reasonable efficacy and safety. Differences in center performance will be ana...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Fiehler, J., Berlis, A., Weber, W., Heuser, L. Tags: SNIS 12th Annual Meeting Oral Abstracts Source Type: research

E-057 Process Improvement in Door-to-Groin Puncture Times at a Comprehensive Stroke Center Shows a Trend Towards Reduced Mortality at 90 Days
ConclusionOur systematic process improvement initiative significantly reduced door-to-groin puncture times and showed a trend towards reduced mortality at 90 days. A multidisciplinary approach and ensuring hospital system investment are key to an effective process.DisclosuresY. Kayan: 2; C; Medtronic, Penumbra. J. Delgado Almandoz: 2; C; Medtronic, Penumbra. M. Young: None. J. Fease: None. J. Scholz: None. A. Milner: None. T. Hehr: None. M. Mulder: None. P. Roohani: None. R. Tarrel: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Kayan, Y., Delgado Almandoz, J., Young, M., Fease, J., Scholz, J., Milner, A., Hehr, T., Mulder, M., Roohani, P., Tarrel, R. Tags: Electronic poster abstracts Source Type: research

E-030 clinical and angiographic outcomes in endovascular treatment of tandem vessel occlusions in acute ischemic stroke
ConclusionEndovascular treatment of tandem arterial occlusions in acute ischemic stroke is feasible, safe, and yields excellent angiographic and good clinical outcomesDisclosuresM. Grigoryan: None. D. Haussen: None. A. Lima: None. J. Grossberg: None. A. Anderson: None. S. Belagaje: None. F. Nahab: None. M. Frankel: None. R. Nogueira: 2; C; Covidien, Steering Committee for the SWIFT and SWIFT Prime Trials and Core Lab for the STAR Trial, Stryker, PI for the TREVO-2 and DAWN Trials, Penumbra, Executive Committee for the 3D Separator Trial.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Grigoryan, M., Haussen, D., Lima, A., Grossberg, J., Anderson, A., Belagaje, S., Nahab, F., Frankel, M., Nogueira, R. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

E-058 Pilot Study: Feasibility of the Use of Ventura Emergency Large Vessel Occlusion Scale to Identify Large Vessel Occlusion Stroke
ObjectivesTo evaluate the feasibility and reliability of a self-designed Ventura Emergency Large Vessel Occlusion (ELVO) Scale performed by Emergency Medical Services (EMS). To identify, if field identification of ELVO, reduces door to groin time.BackgroundEndovascular treatment of stroke is now the standard of care for large vessel occlusion (LVO) stroke within 6 hours of onset. The outcomes of intra-arterial (IA) endovascular treatment are time dependent. The time from arrival to groin vary during the day time versus after hours or infield transfers compared to hospital to hospital transfers. Pre-identification of LVO fr...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Taqi, M., Quadri, S., Suriya, S. Tags: Electronic poster abstracts Source Type: research

Congenital anomaly of the posterior arch of the atlas: a rare risk factor for posterior circulation stroke
We report an extremely rare case involving a posterior arch anomaly of the atlas, causing a vertebral artery dissection (VAD) induced posterior circulation stroke. A 16-year-old girl was admitted to hospital because of new onset dizziness. VAD related multiple infarction in the posterior circulation was revealed. The congenital posterior arch anomaly of the atlas, along with instability of the atlantoaxial joint, were discovered accidentally during follow-up. This is the first case of ischemic stroke related to atlantal posterior arch aplasia and atlantoaxial instability. Although rare, it reminds us that investigation of ...
Source: Journal of NeuroInterventional Surgery - June 16, 2017 Category: Neurosurgery Authors: Ouyang, Z.-y., Qiu, M.-j., Zhao, Z., Wu, X.-b., Tong, L.-s. Tags: Neuroimaging Source Type: research

P005/44 Using the pEGASUS-stent with antithrombogenic properties and single antiplatelet therapy in a case of thrombectomy
IntroductionRescue stenting is used more and more in stroke cases with large-vessel-occlusion or medium-vessel-occlusion refractory to mechanical thrombectomy. The pEGASUS-stent(Phenox) represents a device which is equipped with a hydrophilic polymer coating(HPC) with antithrombogenic properties. The coating allows for implantation under single antiplatelet therapy, thus possibly reducing the risk of bleeding in acute stroke cases.Case HistoryA 79-year-old woman was rushed to emergency room due to left-sided hemiparesis and National-Institutes-of-Health-Stroke-Scale(NIHSS) of 14. Computed-tomography-image showed an occlusi...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Krug, N., Schulze-Zachau, V., Ntoulias, N., Psychogios, M. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

Practice makes perfect: establishing reasonable minimum thrombectomy volume requirements for stroke centers
Introduction Recently, seven randomized controlled trials were published showing benefit to neurothrombectomy (NT) in the setting of anterior circulation emergent large vessel occlusion (ELVO).1–7 Accordingly, the American Heart Association/American Stroke Association has updated societal guidelines and provided a class 1, level of evidence A recommendation that NT be performed in patients with an ELVO who meet appropriate criteria.8 Subsequently, a recent national survey of neurointerventional physicians has suggested increasing procedural volumes, with many reporting increasing indications for patient selection sin...
Source: Journal of NeuroInterventional Surgery - July 12, 2017 Category: Neurosurgery Authors: Fargen, K. M., Fiorella, D. J., Mocco, J. Tags: Editor ' s column Source Type: research

E-055 Internal carotid artery reconstruction with flow diverting stents in the treatment of acute ischemic stroke: technical considerations and medical management
ConclusionsFDS appear to be a safe and effective tool for reconstruction of a symptomatic dissection in tortuous cervical ICAs. Their flexibility allows conformation to complex anatomies and they can be traversed multiple times by aspiration catheters/stentrievers. We found excellent patency at follow up. The unique challenges posed by utilization of high-profile stents in acute stroke require appropriate technical execution and medical management.Disclosures E. Orru: None. F. Bounni: None. M. Marosfoi: None. N. Patel: None. A. Wakhloo: 1; C; Philips medical. 2; C; Stryker, Phenox. 4; C; InNeuroCo, EpiEP, Neural Analytics, ThrombX.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Orru, E., Bounni, F., Marosfoi, M., Patel, N., Wakhloo, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

P-001 Non-contrast CT alone versus combined CT plus CTA or MRA selection for thrombectomy in acute ischemic stroke: analysis of the angel-act registry
DiscussionIn patients selected for MT using non-contrast CT alone versus CT combined with CTA/MRA, we found improved procedural outcomes (shorten door-to-reperfusion time) and similar clinical outcomes and safety profiles. Our real-world findings indicate MT can be safely and effectively performed in hospitals lacking 24/7 access to immediate CTA or MRA. The beneficial effect of using non-contrast CT-only may be present in patients with ultra-early symptoms to ED arrival (within the first hour) and should be further evaluated.Disclosures G. Ma: None. M. Mokin: None. B. Jia: None. A. P. Jadhav: None. X. Tong: None. D. Mo: N...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Ma, G., Mokin, M., Jia, B., Jadhav, A., Tong, X., Mo, D., Ma, N., Gao, F., Huo, X., Luo, G., Song, L., Sun, X., Deng, Y., Wang, A., Zhang, X., Gui, L., Song, C., Peng, Y., Wu, J., Zhao, S., Zhao, J., Zhou, Z., Miao, Z., Ren, Z. Tags: Oral poster abstracts Source Type: research

P-043 Elevated D-dimer levels predicts mortality in COVID-19 with stroke: analysis of multi-center electronic health record data
ConclusionsPeak D-dimer levels above 5.15 µg/ml feu are associated with increased mortality in COVID-19 patients with AIS.Disclosures Y. Kim: None. S. Khose: None. R. Abdelkhaleq: None. S. Salazar-Marioni: None. S. Sheth: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Kim, Y., Khose, S., Abdelkhaleq, R., Salazar-Marioni, S., Sheth, S. Tags: Oral poster abstracts Source Type: research

E-094 Trends in endovascular treatment of cervical artery dissections: a nationwide analysis
ConclusionsDespite an increase in the overall use of endovascular therapy for the treatment of cervical artery dissection in patients with ischemic stroke or TIA, there was no significant association with early clinical outcomes. Future studies looking at long term outcomes including stroke-recurrence are warranted.Disclosures M. Bouslama: None. C. Zhang: None. H. Kamel: 1; C; PI for the NIH-funded ARCADIA trial (NINDS U01NS095869) which receives in-kind study drug from the BMS-Pfizer Alliance for Eliquis® and ancillary study support from Roche Diagnostics. 2; C; Deputy Editor for JAMA Neurology, steering committee mem...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Bouslama, M., Zhang, C., Kamel, H., Merkler, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

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