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Macrocalcification of intracranial vertebral artery may be related to in-stent restenosis: lessons learned from optical coherence tomography
Conclusions This study suggests a potential relationship between macrocalcifications and the risk of in-stent restenosis of the intracranial vertebral artery. These preliminary findings obtained from a limited sample should be verified by prospective large-scale studies.
Source: Journal of NeuroInterventional Surgery - April 19, 2022 Category: Neurosurgery Authors: Xu, R., Yang, B., Li, L., Wang, T., Lu, X., Luo, J., Zhang, X., Dong, J., Wang, Y., Hua, Y., Ma, Y., Jiao, L. Tags: Ischemic stroke Source Type: research

E-131 Transfemoral versus transradial approach for cerebral angiography: A patient preference survey
ConclusionsAt our institution, most patients preferred transradial over transfemoral approach. Most common reasons included pain, recovery time and bruising. Although the effectiveness and safety of transradial approach for non-diagnostic neurointervention remains uncertain and continues to technically evolve, it may be the best option for diagnostic angiograms considering the patients’ preference.Disclosures J. Cappuzzo: None. A. Aguirre: None. A. Monteiro: None. K. Vakharia: None. N. Ruggiero: None. M. Waqas: None. R. Dossani: None. J. Davies: 1; C; National Center for Advancing Translational Sciences of the Nation...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Cappuzzo, J., Aguirre, A., Monteiro, A., Vakharia, K., Ruggiero, N., Waqas, M., Dossani, R., Davies, J., Siddiqui, A., Levy, E. Tags: Electronic poster abstracts Source Type: research

O-017 ADAPT front-line thrombectomy- lessons learned from over 1000 strokes
ConclusionThis study provides a longitudinal overview of the ADAPT MT technique. Medium bore catheters had better performance measures compared to small bore catheters. However, large bore catheters did not show significantly better performance results which suggest a plateau effect.Disclosures S. Al Kasab: None. E. Almallouhi: None. R. Chalhoub: None. A. Alawieh: None. M. Sattur: None. G. Porto: None. E. Bass: None. A. Spiotta: 1; C; Stryker, Penumbra, and Medtronic. 2; C; Stryker, Penumbra, and Terumo.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Al Kasab, S., Almallouhi, E., Chalhoub, R., Alawieh, A., Sattur, M., Porto, G., Bass, E., Spiotta, A. Tags: Oral abstracts Source Type: research

E-067 Institutional trends in mechanical thrombectomy: lessons learned
Conclusions: Preliminary data suggest that thrombectomy is a safe procedure that results in extremely low mortality and significant decreases NIH score over time, which may point to better functional outcome. Overall, there was an improvement in NIHSS reduction with time. Additionally, achieving faster times to recanalization resulted in better improvements in NIHSS. There was a significant difference in the ability of different techniques to achieve first-pass recanalization, though this may reflect clinical judgments about when to use each technique. Producing a TICI score of 3 also improved over time, demonstrating incr...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Trott, S., Vsevolozhskaya, O., Alhajeri, A., Fraser, J. Tags: Electronic Poster Abstracts Source Type: research

Future acute ischemic stroke trials should randomize on the angio table
Perhaps in order to move forward we need to take a lesson from the past. The only two positive randomized trials of intra-arterial therapy to date are PROACT II and MELT.1 2 In both of those cases, randomization occurred on the table, after angiographic confirmation of proximal vessel occlusion. Of patients in PROACT II randomized to a saline infusion, 25% had a good functional outcome (modified Rankin Scale 0–2) at 90 days, compared with 40% of those who received a urokinase infusion. Similarly, in MELT, 23% randomized to saline infusion had modified Rankin Scale 0–1 at 90 days compared with 42% of t...
Source: Journal of NeuroInterventional Surgery - June 11, 2016 Category: Neurosurgery Authors: Jayaraman, M. V., McTaggart, R. A. Tags: Editorials Source Type: research

Correction
Gupta R. Reflections on the lessons of the recent endovascular stroke trials. J NeuroIntervent Surg 2015;7:313. Affiliation number 1 has been removed and replaced with affiliation number 2. The author's correspondence address has also been updated to Rishi Gupta, MD, MBA, Wellstar Medical Group, Neurosurgery, 61 Whitcher Street, Suite 3110, Marietta, GA 30060, USA.
Source: Journal of NeuroInterventional Surgery - May 14, 2015 Category: Neurosurgery Tags: Correction Source Type: research

Reflections on the lessons of the recent endovascular stroke trials
Science is simply common sense at its best, that is, rigidly accurate in observation, and merciless to fallacy in logic. Thomas Henry Huxley As the stroke community is invigorated by the recent results of the four trials showing the overwhelming efficacy of endovascular therapy for large vessel occlusion,1–4 we should reflect upon lessons that were learned that may help future clinical initiatives. It has been almost 16 years since the PROACT-II trial showed a 15% absolute difference in outcomes in patients treated with intra-arterial pro-urokinase for a middle cerebral artery (MCA) occlusion compared with medic...
Source: Journal of NeuroInterventional Surgery - April 13, 2015 Category: Neurosurgery Authors: Gupta, R. Tags: Editor ' s column Source Type: research

Outcomes of tailored angioplasty and/or stenting for symptomatic intracranial atherosclerosis: a prospective cohort study after SAMMPRIS
Conclusions Individualized treatment of ICAD using tailored devices according to arterial access and lesion morphology was feasible and safe in symptomatic patients caused by hypoperfusion with poor collateral flow.
Source: Journal of NeuroInterventional Surgery - April 13, 2015 Category: Neurosurgery Authors: Miao, Z., Song, L., Liebeskind, D. S., Liu, L., Ma, N., Wang, Y., Mo, D., Gao, F., Zhao, X., Dong, K., Zhang, D., Gao, P. Tags: Ischemic stroke Source Type: research