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Stroke care: initial data from a county-based bypass protocol for patients with acute stroke
Conclusions Our results indicate that EMS adaptation of the RA protocol within Lucas County is feasible and effective for early triage and treatment of patients with stroke. Using this protocol, we can significantly improve treatment times for both systemic thrombolysis and MT.
Source: Journal of NeuroInterventional Surgery - June 16, 2017 Category: Neurosurgery Authors: Zaidi, S. F., Shawver, J., Espinosa Morales, A., Salahuddin, H., Tietjen, G., Lindstrom, D., Parquette, B., Adams, A., Korsnack, A., Jumaa, M. A. Tags: Open access, Ischemic stroke Source Type: research

Stroke vision, aphasia, neglect (VAN) assessment--a novel emergent large vessel occlusion screening tool: pilot study and comparison with current clinical severity indices
Conclusions The VAN screening tool accurately identified ELVO patients and outperformed a NIHSS ≥6 severity threshold and may best allow clinical teams to expedite care and mobilize resources for ELVO patients. A larger study to both validate this screening tool and compare with others is warranted.
Source: Journal of NeuroInterventional Surgery - January 12, 2017 Category: Neurosurgery Authors: Teleb, M. S., Ver Hage, A., Carter, J., Jayaraman, M. V., McTaggart, R. A. Tags: Open access, Ischemic stroke Source Type: research

Automated detection of arterial landmarks and vascular occlusions in patients with acute stroke receiving digital subtraction angiography using deep learning
Conclusion These results may serve as an unbiased standard for clinical stroke trials, as optimal standardization would be useful for core laboratories in endovascular thrombectomy studies, and also expedite decision-making during DSA-based procedures.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Khankari, J., Yu, Y., Ouyang, J., Hussein, R., Do, H. M., Heit, J. J., Zaharchuk, G. Tags: Ischemic stroke Source Type: research

EP55 Keep it simple: the SNACE (Sofia non-wire aspiration contrast enhancement) technique for the endovascular management of acute ischemic stroke
We report a prospectively collected clinical experience with a simple technique: SNACE (Sofia Non-wire Aspiration Contrast Enhancement) as the primary method for vessel recanalization.Methods38 prospective patients with ELVO at four institutions were included in the study. The SNACE technique was utilized in all patients. Procedural and clinical data were analyzed.ResultsThe SNACE approach using SOFIA 6 Plus Catheter was successful in achieving Thrombolysis in Cerebral Infarction (TICI) 2b or 3 revascularizations in 88% of cases. The first Pass effect was obtained in 75%. The average time from groin puncture to at least TI...
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Pabon, B., Torres, V., Mejia, J., Patino, M., Vargas, O., Serna, N., Pelaez, J. Tags: Treatment Source Type: research

Development of a machine learning-based real-time location system to streamline acute endovascular intervention in acute stroke: a proof-of-concept study
Conclusions ML-based RTLS technology using WiFi fingerprinting has the potential to streamline delivery of acute stroke endovascular intervention by efficiently tracking patient and staff movement during stroke calls.
Source: Journal of NeuroInterventional Surgery - July 14, 2022 Category: Neurosurgery Authors: Lim, D. Z., Yeo, M., Dahan, A., Tahayori, B., Kok, H. K., Abbasi-Rad, M., Maingard, J., Kutaiba, N., Russell, J., Thijs, V., Jhamb, A., Chandra, R. V., Brooks, M., Barras, C., Asadi, H. Tags: Vascular neurology Source Type: research

O-023 Stroke predictX: a tissue-based clinical decision tool to predict stroke outcomes after endovascular therapy
ConclusionsOur pre-and post-procedural models reliably estimated clinical outcomes in stroke patients undergoing thrombectomy. They represent a step forward in creating simple and efficient prognostication tools to aid treatment decision-making.Disclosures M. Bouslama: None. L. Pisani: None. D. Haussen: 2; C; Stryker, Vesalio, Cerenovus, and Jacobs Institute. 4; C; VizAi. R. Nogueira: 1; C; PI of ENDOLOW trial. Funding provided by Cerenovus. 2; C; consulting fees for advisory roles with Anaconda, Biogen, Cerenovus, Genentech, Hybernia, Imperative Care, Medtronic, Phenox, Philips, Prolong Pharmaceuticals, Stryker Neurovascu...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Bouslama, M., Pisani, L., Haussen, D., Nogueira, R. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

Training Guidelines for Endovascular Ischemic Stroke Intervention: An International multi-society consensus document
Background Ischemic stroke is a leading cause of death and disability worldwide. Much of the long-term disability occurs in patients with Emergent Large Vessel Occlusion (ELVO). In fact, in these patients, occlusion of a major intracerebral artery results in a large area of brain injury often resulting in death or severe disability.1 Until recently, intravenous tissue plasminogen activator (t-PA) was the only proven treatment for ELVO. However, the landscape of stroke treatment has changed with the publication of five randomized multicenter controlled clincal trials. These trials provide Class 1, Level A evidence that endo...
Source: Journal of NeuroInterventional Surgery - September 12, 2016 Category: Neurosurgery Tags: Open access, Standard Standards Source Type: research

P81 Novel synthetic clot analogs for in-vitro stroke modelling
ConclusionSelected synthetic clots can successfully be implemented in an in-vitro training environment of mechanical thrombectomy. The clots’ different properties might serve to mimic fibrin-rich and red blood cell human thrombi.ReferencesNadine Wortmann, Thomas Andersek, Helena Guerreiro, et al. Development of Synthetic Thrombus Models to Simulate Stroke Treatment in a Physical Neurointerventional Training Model, All Life 2022;15:1, 283–301, DOI:10.1080/26895293.2022.2046181Spallek J, Kuhl J, Wortmann N, et al. Design for Mass Adaptation of the Neurointerventional Training Model Hannes with Patient-specific An...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guerreiro, H., Wortmann, N., Andersek, T., Ngo, T., Frölich, A., Krause, D., Fiehler, J., Kyselyova, A., Flottmann, F. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P-008 Probabilistic ensemble learning for prediction of stroke thrombectomy outcomes from the neurovascular quality initiative-quality outcomes database (NVQI-QOD) registry
ConclusionsThis study demonstrates the utility of probabilistic ensemble learning in clinical decision-making and prognosis. It can provide robust predictions as well as quantify data uncertainty. Our results regarding NIHSS changes reinforce the substantial benefits of MT, that can improve outcomes in nearly half of patients. The degree of disability relevant to the 90-day follow-up mRS can be determined by probabilistic learning available as early as discharge.Disclosures C. Zhou: None. S. Faruqui: None. A. Patel: None. R. Abdalla: None. A. Shaibani: None. M. Potts: None. B. Jahromi: None. S. Ansari: None. D. Cantrell: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Zhou, C., Faruqui, S., Patel, A., Abdalla, R., Shaibani, A., Potts, M., Jahromi, B., Ansari, S., Cantrell, D. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

Novel methodology to replicate clot analogs with diverse composition in acute ischemic stroke
Conclusions Seven different clot types were developed to replicate common AIS thrombi. These clot analogs may be beneficial for the preclinical evaluation of endovascular therapies, and may be applied to interventional technique training.
Source: Journal of NeuroInterventional Surgery - April 13, 2017 Category: Neurosurgery Authors: Duffy, S., Farrell, M., McArdle, K., Thornton, J., Vale, D., Rainsford, E., Morris, L., Liebeskind, D. S., MacCarthy, E., Gilvarry, M. Tags: Basic science Source Type: research

P74 Keep it simple: MAC (Manual Aspiration with Contrast) technique for the endovascular management of acute ischemic stroke (LVO & MVO)
We report a prospectively collected clinical experience with a simple technique: MAC (Manual Aspiration Contrast Enhancement) as the primary method for vessel recanalization.Gently contrast injection while the aspiration catheter is advancedto the thrombus and subsequentlycreating a closed-loop system with the contrast column within the cathetercan result in better visualization during the aspiration, thus improving the FPEavoiding clot fragmentation, multiple passes and blind movements of catheter by a single operator.Methods47 prospectively patients with ELVO and 3 cases of middle vessel occlusion (MVO) at four instituti...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Pabon, B., Torres, V., Patino, M., Pelaez, F., Mutis, J. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

E-045 Nihss and its component subscores are suboptimal predictors with colinearity
Conclusions NIHSS composite score is a suboptimal predictor for assessed patient outcomes. Principal component analysis improves predictive value of assessment with a statistically significant effect for pre-intervention patient outcomes analysis. Statistically significant variables are heavily dependent of NIHSS subscores, and variation in the distribution of these subscore may represent a significant source of bias. References . OA Berkhemer, et al. MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: new england journal of med 372;1 nejm.org january 1...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Arndt, S., Albar, A., Bennett, G., Lavie, J., Gulotta, P., Milburn, J. Tags: Electronic Poster Abstracts Source Type: research

In defense of our patients
We read with interest and dismay the article ‘Public health urgency created by the success of mechanical thrombectomy studies in stroke’ recently published in Circulation.1 There is now overwhelming, class 1, level A evidence supporting mechanical thrombectomy (MT) as the standard of care for eligible patients with acute stroke secondary to an emergent large vessel occlusion (ELVO). We agree that attention must be focused on how to translate this evidence into better outcomes for more patients. However, the opinions expressed by Drs Hopkins and Holmes lead to unwarranted conclusions that have dangerous implicat...
Source: Journal of NeuroInterventional Surgery - May 30, 2017 Category: Neurosurgery Authors: Hussain, S., Fiorella, D., Mocco, J., Arthur, A., Linfante, I., Zipfel, G., Woo, H., Frei, D., Nogueira, R., Albuquerque, F. C., on behalf of the Society of NeuroInterventional Surgery, the Cerebrovascular Section of the American Association of Neurologic Tags: Editorials Source Type: research

O16 Mechanical thrombectomy practices in Europe: results from an international survey from the ESMINT society
ConclusionsThis European survey emphasizes the variety of practices regarding thrombectomy at the level of countries, centers and across practitioners. Even if most centers remain understaffed to ensure actual and future needs for MT, most of TCSC are actively training young INR.ReferencesGoyal, Mayank et al. "Endovascular Thrombectomy after Large-vessel Ischaemic Stroke: A Meta-analysis of Individual Patient Data from Five Randomised Trials."Lancet (London, England) Vol. 387,10029 (2016): 1723–31. DOI:10.1016/S0140-6736(16)00163-X Do you have any conflict of interest to declare?: No
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Forestier, G., Kaesmacher, J., Boulouis, G., Hanning, U., Zelenak, K., Januel, A., Kulczar, Z., Fiehler, J., Rouchaud, A., ESMINT Research Committee, EYMINT Collaborative Group Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

E-071 Organization of a Neurointerventional Fellowship Curriculum
The objective of this report is to present a comprehensive three -tier model for a Neurointerventional didactics program. Methods The model divides an annual Neurointerventional didactic curriculum in to three tiers: Introduction to Neurointervention Series: Basic concepts of Neurointervention. Implemented during the first two months of the academic year. Faculty/speaker driven. Total 20 sessions. See Table 1. Neurointervention Core Curriculum: Implemented during months 3 to 12 of the academic year. Faculty/speaker moderated; more interactive. Total 30 sessions. See. Table 2. Neurointervention Advanced Didactics: Period...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Garg, A. Tags: Electronic poster abstracts Source Type: research

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