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O-042 Complications of DAPT cessation at 3 months versus 6 months after flow diversion of unruptured intracranial aneurysms
ConclusionsOnly 0.6% (n=1) of patients exhibited complications after 3 month follow-up. We conclude that DAPT duration of 3 months after endoluminal flow diversion of unruptured cerebral aneurysms of the anterior circulation is not associated with increased rates of hemorrhagic or thromboembolic complications compared to a traditional 6-month regimen.Disclosures S. Srinivasan: None. A. White: None. M. Al-Abdulkareem: None. J. Barr: None. L. Pride: None. J. White: None. R. Novakovic-White: None. R. Sillero: None. B. Welch: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Srinivasan, S., White, A., Al-Abdulkareem, M., Barr, J., Pride, L., White, J., Novakovic-White, R., Sillero, R., Welch, B. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

E-219 Direct vs indirect revascularization for moyamoya: a large multicenter study
ConclusionSince both modalities showed comparable rates of overall total strokes, both modalities of revascularization can be performed depending on the patient’s risk assessment.Abstract E-219 Table 1Direct Indirect Effect variable Value (95% confidence interval) P-value Primary Outcome Symptomatic stroke, n (%) 23/198 (11.6) 19/198 (9.6) Odds ratio 1.238 (0.651 - 2.354) 0.514 Secondary Outcomes Symptomatic ischemic stroke, n (%) 23/198 (11.6) 16/198 (8.1) Odds ratio 1.495 (0.764 - 2.924) 0.240 Symptomatic hemorrhagic stroke, n (%) 0/198 (0) 3/198 (1.5) –– –– 0.248 Peri-operative stroke,...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: El Naamani, K., Chen, C., Jabre, R., Saad, H., Grissberg, J., Dmytriw, A., Patel, A., Khorasanizadeh, M., Ogilvy, C., Thomas, A., Monteiro, A., Siddiqui, A., Cortez, G., Hanel, R., Porto, G., Spiotta, A., Piscopo, A., Hasan, D., Ghorbani, M., Weinberg, J. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device
Conclusion To our knowledge, this is the most extensive study to date that compares the treatment of different intracranial bifurcation aneurysms using the WEB device. Basilar tip and ICA bifurcation aneurysms showed significantly higher rates of aneurysm occlusion than other locations.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Adeeb, N., Dibas, M., Diestro, J. D. B., Phan, K., Cuellar-Saenz, H. H., Sweid, A., Lay, S. V., Guenego, A., Aslan, A., Renieri, L., Sundararajan, S. H., Saliou, G., Möhlenbruch, M., Regenhardt, R. W., Vranic, J. E., Lylyk, I., Foreman, P. M., Vac Tags: Hemorrhagic stroke Source Type: research

Bifurcation geometry remodelling of vessels in de novo and growing intracranial aneurysms: a multicenter study
Conclusion Our study suggests that wider bifurcation angles that have long been deemed causal factors for IA formation or growth may be secondary to IA formation at pathologic bifurcation sites. This finding has implications for our understanding of IA formation pathophysiology.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Boucherit, J., Kerleroux, B., Boulouis, G., Tessier, G., Rodriguez, C., Sporns, P. B., Ghannouchi, H., Shotar, E., Gariel, F., Marnat, G., Burel, J., Ifergan, H., Forestier, G., Rouchaud, A., Desal, H., Nouri, A., Autrusseau, F., Loirand, G., Bourcier, R. Tags: Hemorrhagic stroke Source Type: research

Endovascular therapy may not be beneficial for patients with mild acute ischemic stroke compared to best medical management
We read with great interest the meta-analysis by Lin et al on the comparison of the clinical effectiveness between endovascular therapy (EVT) and best medical management (BMM) in patients with mild acute ischemic stroke (AIS).1 The study is of profound academic importance, and there are some points that we would like to address. In the "Statistical analyses" section, the authors described how they pooled data across studies by using the fixed effects model based on an inverse variance method. Subsequently, in the "Results – Primary outcome" section, the authors stated that for AIS patients with National Institutes of...
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Zheng, F., von Spreckelsen, N., Hu, W. Tags: Letter Source Type: research

Perceived acceptable uncertainty regarding comparability of endovascular treatment alone versus intravenous thrombolysis plus endovascular treatment
Conclusion Physicians would generally feel comfortable skipping IVT before EVT at different certainty thresholds. Most physicians would treat with EVT alone if randomized trial data suggested that the number of patients achieving functional independence at 90 days was similar between the two groups, and one could be sufficiently sure that no more than 3 out of 100 patients would not achieve functional independence at 90 days due to skipping IVT.
Source: Journal of NeuroInterventional Surgery - February 14, 2023 Category: Neurosurgery Authors: Kaesmacher, J., Mujanovic, A., Treurniet, K., Kappelhof, M., Meinel, T. R., Yang, P., Liu, J., Zhang, Y., Zi, W., Yang, Q., Nogueira, R. G., Kimura, K., Matsumaru, Y., Suzuki, K., Yan, B., Mitchell, P. J., Miao, Z., Roos, Y. B. W. E. M., Majoie, C. B. L. Tags: Open access, Ischemic stroke Source Type: research

P77 Predictors of good clinical outcome after thrombectomy for distal medium vessel occlusions
ConclusionAn older age, a longer puncture to recanalization time and a higher baseline core volume were strongly associated with poor clinical outcomes, while successful recanalization (mTICI 2c-3) was associated with better outcomes after MT for DMVO.ReferencesGuenego A, Mine B, Bonnet T, et al. Thrombectomy for distal medium vessel occlusion with a new generation of stentretriever (tigertriever 13). Interv Neuroradiol 2021: 15910199211039926. 2021/09/14. DOI: 10.1177/15910199211039926. Do you have any conflict of interest to declare?: YesConflict of Interest StatementConsultancy for Rapid Medical (travel grant only)
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P79 Multicenter assessment of the Tigertriever 13 for thrombectomy in primary medium vessels occlusions
ConclusionMechanical thrombectomy using the Tigertriever 13 appears to be safe and effective for MeVO among different centers and physicians, as a first-line device or as a recue-therapy after an other approach failure.ReferencesGuenego A, Mine B, Bonnet T, et al. Thrombectomy for distal medium vessel occlusion with a new generation of stentretriever (tigertriever 13). Interv Neuroradiol 2021: 15910199211039926. 2021/09/14. DOI: 10.1177/15910199211039926. Do you have any conflict of interest to declare?: YesConflict of Interest StatementConsultancy for Rapid Medical (travel grant only)
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B., Dmytriw, A., Regenhardt, R., Diestro, J., Jabbour, P., Siegler, J., Gonzalez, N., Levitt, M., Tancredi, I., Rouchaud, A., Fiehler, J., Kan, P., Berge, J., Nedelcu, S., Ota, T., Yeo, L., Sheth, S., Collin, T., Renieri, L., Mowla, A Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

LB003 Multicenter assessment of the tigertriever 13 for thrombectomy in primary medium vessels occlusions
ConclusionMechanical thrombectomy using the Tigertriever13 appears to be safe and effective for MeVO among different centers and physicians, as a first-line device or as a recue-therapy after an other approach failure.Disclosures A. guenego: 6; C; Travel Grant to PAIRS in Dubai by Rapid Medical. B. lubicz: None. A. Dmytriw: None. R. Regenhardt: None. J. diestro: None. V. pereira: None. P. jabbour: None. J. siegler: None. N. gonzalez: None. M. Levitt: None. I. Tancredi: None. A. Rouchaud: None. J. Fiehler: None. T. Faizy: None. P. Kan: None. X. barreau: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B., Dmytriw, A., Regenhardt, R., Diestro, J., Pereira, V., Jabbour, P., Siegler, J., Gonzalez, N., Levitt, M., Tancredi, I., Rouchaud, A., Fiehler, J., Faizy, T., Kan, P., Barreau, X. Tags: SNIS 19th annual meeting late-breaking oral abstracts Source Type: research

E-095 First-pass effect predicts clinical outcome and infarct growth after thrombectomy for distal medium vessel occlusions
Conclusion mFPE is associated with better clinical outcomes and lower stroke progression in DMVO.Disclosures A. Guenego: None. B. Lubicz: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Guenego, A., Lubicz, B. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-137 Endovascular therapy delay for acute large vessel occlusion is associated with worse functional outcome and increased mortality
ConclusionShorter times to MT and reperfusion impact functional outcome and mortality in LVO stroke patients. This indicates that an adequate hospital protocol and continuous education may lead to faster and more efficient stroke activations leading to a shorter time to MT and eventual reperfusion. Goals of door-to-puncture must be established in order to achieve better outcomes.Disclosures J. Carrion-Penagos: None. R. Morsi: None. S. Thind: None. E. Coleman: None. J. Brorson: None. C. McKoy: None. S. Mendelson: None. S. Prabhakaran: None. A. Mansour: None. T. Kass-Hout: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Carrion-Penagos, J., Morsi, R., Thind, S., Coleman, E., Brorson, J., McKoy, C., Mendelson, S., Prabhakaran, S., Mansour, A., Kass-Hout, T. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-138 Intracerebral hemorrhage in patients transferred for mechanical thrombectomy
ConclusionsIn a large series of stroke patients being specifically transferred for mechanical thrombectomy, the rate of ICH on arrival to the thrombectomy hospital was 1.2%. In less than 50% of those cases the decision to forgo intervention was related to the ICH finding. The results of our study adds to the concerns that repeat imaging delays treatment by demonstrating that the incidence of ICH is low, which may warrant reconsideration of current stroke workflows for large vessel occlusion transfers.Disclosures Y. Radaideh: None. K. Joshi: None. M. Chen: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Radaideh, Y., Joshi, K., Chen, M. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

P-015 Implementation of a cognitive dysfunction screening protocol after aneurysmal subarachnoid hemorrhage
ConclusionWe successfully implemented an evidence-based screening protocol for cognitive dysfunction after aSAH. Most of these patients did exhibit cognitive dysfunction using the MoCA despite a good functional recovery, defined as mRS score <2. Screening only with the mRS is inadequate to identify the substantial cognitive dysfunction within this patient population. Further research is necessary to understand the impact of early cognitive intervention on long term outcomes for patients with cognitive impairment following aSAH.Disclosures N. Hall: None. J. Jackson: None. R. Chitale: None. M. Fusco: None. C. Considine: N...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Hall, N., Jackson, J., Chitale, R., Fusco, M., Considine, C., Froehler, M. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

P-019 Comparative effectiveness of stent-assisted coiling and woven endobridge (WEB) embolization for the treatment of unruptured wide-neck bifurcation intracranial aneurysms
ConclusionMid-term complete and adequate occlusion rates were similar between patients treated with WEB and SAC. Given the comparable outcomes, there may be equipoise in treatment options for WNBAs.Abstract P-019 Table 1Baseline patient and aneurysm morphology parameters between treatment groups Aneurysm parameters* WEB (n=27) Stent-coil (n=54) p-value Age 63 (50–69) 65 (57–69) 0.511 Gender, male 6 (22%) 12 (22%) 1.000 Smoking Status Current smoker 9 (33%) 9 (17%) 0.235 Prior Smoker 9 (33%) 22 (41%) Never Smoker 9 (33%) 23 (43%) Location Acomm 9 (33%) 20 (37%) 0.772 Basilar apex 6 (22%) 17 (32%) Carotid termin...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Kashkoush, A., Desai, A., Davison, M., Achey, R., Mahapatra, A., Patterson, T., Moore, N., Bain, M. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

P-032 Underlying intracranial atherosclerotic disease is associated with worse outcomes in acute large vessel occlusion undergoing endovascular therapy
ConclusionUnderlying ICAD is associated with a 2.7-fold increase in the odds of mortality and a 4.5-fold (1/0.22) increase in unfavorable functional outcome at 90 days in patients with LVO undergoing traditional MT. Further research is warranted to understand factors associated with poor outcomes and investigate alternative interventional approaches and medical management in this high-risk population.Disclosures S. Thind: None. R. Morsi: None. T. Karrison: None. E. Coleman: None. J. Brorson: None. C. McKoy: None. S. Mendelson: None. A. Mansour: None. S. Prabhakaran: None. T. Kass-Hout: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Thind, S., Morsi, R., Karrison, T., Coleman, E., Brorson, J., McKoy, C., Mendelson, S., Mansour, A., Prabhakaran, S., Kass-Hout, T. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

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