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Source: Journal of NeuroInterventional Surgery
Condition: Thrombosis

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Total 240 results found since Jan 2013.

E-236 Comparison of pipeline vs surpass flow diverter: a single center experience
ConclusionsIn our single-center retrospective experience in the last 5 years, the Pipeline and Surpass were comparable except that the Surpass flow diverter cases tended to have a higher baseline aneurysm width compared to Pipeline. However, the procedural outcomes and complication rates were comparable between both groups. Long-term and follow-up data to be evaluated for efficacy outcomes assessment.Disclosures A. Pandhi: None. A. Kashkoush: None. M. Bain: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Pandhi, A., Kashkoush, A., Bain, M. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

E-237 A 911 continuation of care protocol reduces door in, door out time for transfer patients with emergent large vessel occlusion
ConclusionUtilizing the 911 COC process for EMS transport of patients eligible for MT reduced DIDO time at the sending hospital, which may contribute to improved functional outcome.Disclosures R. Shaw: None. H. Rho: None. N. Sangha: None. J. Saver: 4; C; BrainQ, Clinical Trial Steering Committee. 6; C; Abbott, Clinical Trial Steering Committee, Medtronic, Clinical Trial Steering Committee, BrainsGate, Clinical Trial Steering Committee, Boehringer-Ingelheim (Prevention Only), Clinical Trial Steering Committee, Cerenovus, Clinical Trial Steering Committee, Phagenesis, Clinical Trial Steering Committee. C. Liang: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Shaw, R., Rho, H., Sangha, N., Saver, J., Liang, C. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research

Endovascular treatment for cerebral venous thrombosis: current status, challenges, and opportunities
Cerebral venous thrombosis (CVT) mostly affects young people. So far, endovascular treatment (EVT) has not been shown to be beneficial in CVT, partially because venous EVT tools are not yet fully optimized, and therefore EVT is only used as a rescue treatment in rare cases. Identifying a subgroup of CVT patients that could benefit from EVT is challenging, given the milder course of disease compared with acute ischemic stroke, the paucity of data on prognostic factors (both in the clinical and imaging domain), and the lack of consensus on what constitutes 'technical success' in CVT EVT. In this review, we discuss the major ...
Source: Journal of NeuroInterventional Surgery - July 14, 2022 Category: Neurosurgery Authors: Goyal, M., Fladt, J., Coutinho, J. M., McDonough, R., Ospel, J. Tags: Vascular neurology Source Type: research

Thrombectomy for secondary distal, medium vessel occlusions of the posterior circulation: seeking complete reperfusion
Conclusion Thrombectomy for secondary posterior circulation DMVO seems to be safe and technically feasible. Even though thrombi that have migrated preprocedurally may be easier to retract, successful reperfusion can be achieved in the majority of patients with secondary DMVO of the P2 and P3 segment.
Source: Journal of NeuroInterventional Surgery - June 16, 2022 Category: Neurosurgery Authors: Meyer, L., Stracke, C. P., Wallocha, M., Broocks, G., Sporns, P. B., Piechowiak, E. I., Kaesmacher, J., Maegerlein, C., Dorn, F., Zimmermann, H., Naziri, W., Abdullayev, N., Kabbasch, C., Behme, D., Jamous, A., Maus, V., Fischer, S., Möhlenbruch, Tags: Ischemic stroke Source Type: research

Analysis of microRNA signatures in ischemic stroke thrombus
Conclusions The microRNA expression pattern can provide information regarding the mechanism of stroke by reflecting the underlying pathological status of the organ from which the thrombus was derived.
Source: Journal of NeuroInterventional Surgery - April 19, 2022 Category: Neurosurgery Authors: Kim, J.-M., Byun, J.-S., Kim, J., Park, M.-S., Hong, S. A., Nam, T.-K., Choi, H. H., Hong, S., Han, S.-H., Jeong, H.-B., Park, K.-Y., Kim, H. R. Tags: Ischemic stroke Source Type: research

Early recanalization in large-vessel occlusion stroke patients transferred for endovascular treatment
Conclusions Early recanalization is associated with clinical improvement between PSC and CSC admission, more distal occlusions and shorter thrombi at baseline imaging, and better functional outcome.
Source: Journal of NeuroInterventional Surgery - April 19, 2022 Category: Neurosurgery Authors: Arrarte Terreros, N., Bruggeman, A. A. E., Swijnenburg, I. S. J., van Meenen, L. C. C., Groot, A. E., Coutinho, J. M., Roos, Y. B. W. E. M., Emmer, B. J., Beenen, L. F. M., van Bavel, E., Marquering, H. A., Majoie, C. B. L. M. Tags: Open access Vascular neurology Source Type: research

Analysis of microRNA signatures in ischemic stroke thrombus
Conclusions The microRNA expression pattern can provide information regarding the mechanism of stroke by reflecting the underlying pathological status of the organ from which the thrombus was derived.
Source: Journal of NeuroInterventional Surgery - April 12, 2022 Category: Neurosurgery Authors: Kim, J.-M., Byun, J.-S., Kim, J., Park, M.-S., Hong, S. A., Nam, T.-K., Choi, H. H., Hong, S., Han, S.-H., Jeong, H.-B., Park, K.-Y., Kim, H. R. Tags: Ischemic stroke Source Type: research

Early recanalization in large-vessel occlusion stroke patients transferred for endovascular treatment
Conclusions Early recanalization is associated with clinical improvement between PSC and CSC admission, more distal occlusions and shorter thrombi at baseline imaging, and better functional outcome.
Source: Journal of NeuroInterventional Surgery - April 12, 2022 Category: Neurosurgery Authors: Arrarte Terreros, N., Bruggeman, A. A. E., Swijnenburg, I. S. J., van Meenen, L. C. C., Groot, A. E., Coutinho, J. M., Roos, Y. B. W. E. M., Emmer, B. J., Beenen, L. F. M., van Bavel, E., Marquering, H. A., Majoie, C. B. L. M. Tags: Open access Vascular neurology Source Type: research

Histological evaluation of acute ischemic stroke thrombi may indicate the occurrence of vessel wall injury during mechanical thrombectomy
Conclusions Histological markers of VWI were present in 12% of AIS thrombi, suggesting that VWI might be related to MT. VWI was associated with soft thrombus consistency, higher number of passes and poorer revascularization outcome. There was no significant correlation between VWI and MT device.
Source: Journal of NeuroInterventional Surgery - March 18, 2022 Category: Neurosurgery Authors: Mereuta, O. M., Abbasi, M., Fitzgerald, S., Dai, D., Kadirvel, R., Hanel, R. A., Yoo, A. J., Almekhlafi, M. A., Layton, K. F., Delgado Almandoz, J. E., Kvamme, P., Mendes Pereira, V., Jahromi, B. S., Nogueira, R. G., Gounis, M. J., Patel, B., Aghaebrahim, Tags: Open access, Ischemic stroke Source Type: research

A lower admission level of interleukin-6 is associated with first-pass effect in ischemic stroke patients
Conclusion A lower admission level of IL-6 is associated with FPE.
Source: Journal of NeuroInterventional Surgery - February 16, 2022 Category: Neurosurgery Authors: Mechtouff, L., Bochaton, T., Paccalet, A., Crola Da Silva, C., Buisson, M., Amaz, C., Derex, L., Ong, E., Berthezene, Y., Dufay, N., Ovize, M., Mewton, N., Cho, T.-H., Nighoghossian, N., Eker, O. F. Tags: Vascular neurology Source Type: research

Bailout stentectomy of 47 self-expandable intracranial stents
Conclusion While various single devices can be used to safely retrieve dysfunctional intracranial self-expandable stents, dual-device techniques are more than twice as effective, according to our experience.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Chapot, R., Stracke, C. P., Wallocha, M., Rikhtegar, R., Yamac, E., Mosimann, P. J. Tags: Open access, New devices New devices and techniques Source Type: research

Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition
Conclusion LAA clots are larger and associated with a large red blood cell-rich extracted clot area, suggesting soft thrombus material. Cardioembolic clots are smaller in the extracted clot area, consistent in composition and area across passes, and have higher fibrin and platelets/other content than LAA clots, making them stiffer clots. The per-pass histological composition and extracted clot area of cryptogenic clots are similar to those of cardioembolic clots, suggesting similar formation mechanisms.
Source: Journal of NeuroInterventional Surgery - November 18, 2021 Category: Neurosurgery Authors: Fitzgerald, S., Rossi, R., Mereuta, O. M., Jabrah, D., Okolo, A., Douglas, A., Molina Gil, S., Pandit, A., McCarthy, R., Gilvarry, M., Dunker, D., Nordanstig, A., Ceder, E., Redfors, P., Jood, K., Dehlfors, N., Magoufis, G., Tsivgoulis, G., Brinjikji, W., Tags: Open access, Ischemic stroke Source Type: research

Dual-roadmap guidance for endovascular recanalization of medically refractory non-acute intracranial arterial occlusions: consecutive multicenter series and technical review
Conclusions Endovascular recanalization of non-acute intracranial occlusions can be performed with a high rate of technical success and few complications with assistance of the dual-roadmap technique for navigation. Four types of dual-roadmap schemes provide technical references.
Source: Journal of NeuroInterventional Surgery - September 15, 2021 Category: Neurosurgery Authors: Gao, F., Guo, X., Sun, X., Liu, Y., Wu, Y., Miao, Z. Tags: Ischemic stroke Source Type: research

High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke
Conclusions 3D-SEM provides novel and potentially clinically relevant information on clot components and ultrastructure which may help to inform thrombolytic treatment and medical device design.
Source: Journal of NeuroInterventional Surgery - September 15, 2021 Category: Neurosurgery Authors: Mereuta, O. M., Fitzgerald, S., Christensen, T. A., Jaspersen, A. L., Dai, D., Abbasi, M., Puttappa, T., Kadirvel, R., Kallmes, D. F., Doyle, K. M., Brinjikji, W. Tags: Ischemic stroke Source Type: research

EP46* First pass effect and associated clot characteristics in the EXCELLENT registry - Interim analysis
ConclusionsThe high rate of ‘real-world’ FPE observed in EXCELLENT was associated with improved clinical outcomes. Clots retrieved with FPE had higher RBC and lower fibrin content compared to non FPE and to first pass mTICI <2c/3 e. These preliminary findings await confirmation from analysis of the full dataset.DisclosureEXCELLENT is sponsored by Cerenovus. Dr. Jovin is a consultant for Neuravi, Codman Neurovascular, Stryker (PI DAWN; unpaid), Fundacio Ictus (PI REVASCAT; unpaid), and holds stock in Anaconda, Silk Road, and Blockade Medical.
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Jovin, T., Nogueira, R., Siddiqui, A., Yoo, A., Hanel, R., Zaidat, O., Hacke, W., Fiehler, J., De Meyer, S., Brinjikji, W., Doyle, K., Liebeskind, D., Haussen, D., Inoa, V., Humphries, W., Woodward, K., Jabbour, P., Francois, O., Levy, E., Bozorgchami, H. Tags: Treatment Source Type: research