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Revisiting the NIH Stroke Scale as a screening tool for proximal vessel occlusion: can advanced imaging be targeted in acute stroke?
Conclusions In this cohort, specific NIHSS criteria were highly sensitive for emergent large vessel occlusion and, if validated, may allow for clinical screening prior to advanced imaging with CT angiography.
Source: Journal of NeuroInterventional Surgery - November 14, 2016 Category: Neurosurgery Authors: Moore, R. D., Jackson, J. C., Venkatesh, S. L., Quarfordt, S. D., Baxter, B. W. Tags: Ischemic stroke Source Type: research

Different risk factors for poor outcome between patients with positive and negative susceptibility vessel sign
Conclusions The risk factors for clinical outcome after IVT in patients with negative SVS may differ from those with positive SVS.
Source: Journal of NeuroInterventional Surgery - September 12, 2016 Category: Neurosurgery Authors: Yan, S., Liu, K., Tong, L., Yu, Y., Zhang, S., Lou, M. Tags: Ischemic stroke Source Type: research

Mechanical thrombectomy versus systemic thrombolysis in MCA stroke: a distance to thrombus-based outcome analysis
Conclusions In patients with an acute MCA occlusion and a DT <16 mm, IVT–MT leads to a significantly better outcome than in patients treated with IVT alone.
Source: Journal of NeuroInterventional Surgery - August 11, 2016 Category: Neurosurgery Authors: Lobsien, D., Gawlitza, M., Schaudinn, A., Schob, S., Hobohm, C., Fritzsch, D., Quäschling, U., Hoffmann, K.-T., Friedrich, B. Tags: Ischemic stroke Source Type: research

Validation of the Modified Raymond-Roy classification for intracranial aneurysms treated with coil embolization
Conclusions This study confirms that the MRRC enhances the predictive accuracy of the RROC.
Source: Journal of NeuroInterventional Surgery - August 11, 2016 Category: Neurosurgery Authors: Stapleton, C. J., Torok, C. M., Rabinov, J. D., Walcott, B. P., Mascitelli, J. R., Leslie-Mazwi, T. M., Hirsch, J. A., Yoo, A. J., Ogilvy, C. S., Patel, A. B. Tags: Hemorrhagic stroke Source Type: research

In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow
Conclusions These experiments suggest that aspiration is only effective if the catheter tip is in direct contact with the thrombus. If the catheter tip is not in contact with the thrombus, aspirate is drawn from the vessels proximal of the occlusion. This could affect collateral flow in vivo.
Source: Journal of NeuroInterventional Surgery - August 11, 2016 Category: Neurosurgery Authors: Lally, F., Soorani, M., Woo, T., Nayak, S., Jadun, C., Yang, Y., McCrudden, J., Naire, S., Grunwald, I., Roffe, C. Tags: Basic science Source Type: research

E-019 Outcome of the Patients Presenting with Basilar Occlusions in a Busy Stroke Center Treated with new Generation Stent Retrievers
ConclusionAlthough the successful recanalization rate (TICI 2 b or higher) in basilar occlusions is high (18/23 (78.3%)), the mortality (10/23 (43%)) and morbidity with MRS ≥ 3 (5/23 (22%)) remains disappointingly high. In our study, good clinical outcome (MRS 0–2) was achieved in 30% (7/23) of patients, better than the natural course in basilar occlusions, which is encouraging. This group highlights the value of early presentation and a negative CT as strong predictors of a good outcome. The prognosis in patients with basilar occlusions with positive CT findings and unknown time of onset remain guarded.Disclosure...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Akhtar, I., Halpin, J., Holloway, W., Martin, C., Akhtar, N. Tags: Electronic poster abstracts Source Type: research

O-011 Symptomatic Intracranial Hemorrhage After Reperfusion Therapy - Impact of Definition on its Frequency
ConclusionUnder the trial definition, any apparent extravascular blood in the brain or cranium with an increase of 4 or more on the NIHSS, associated or not, is considered a sICH; as a result, the inclusion of hemorrhagic infarctions (HI1 and HI2) in this definition resulted in an apparent relative increase in sICH rates. Subjecting the THERAPY cohort to other definitions yielded notable variance in complication rates. As there is no current standardization for the quantification of sICH, further analysis and data are needed to identify and standardize a succinct and relevant definition.DisclosuresR. von Kummer: 2; C; Penu...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: von Kummer, R., Frei, D., Yoo, A., Zaidat, O., Khatri, P., Gupta, R., Lopes, D., Shownkeen, H., Meyer, D., Buell, H., Bach, V., Kuo, S., Bose, A., Sit, S., Mocco, J. Tags: Oral abstracts Source Type: research

O-012 Emergent Endovascular Management of Long-segment Carotid Artery Dissections in Acute Ischemic Stroke Intervention with Multiple Tandem Stents
ConclusionTandem stent reconstruction for the treatment of long segment and flow limiting carotid dissections is technically safe and effective with favorable clinical outcomes in acute ischemic stroke intervention, allowing for successful thrombectomy, vessel salvage, restoration of cerebral perfusion, and prevention of recurrent thromboembolic stroke.DisclosuresS. Ansari: None. A. Kuhn: None. A. Honarmand: None. S. Hou: None. M. Khan: None. J. Chueh: None. I. van der Bom: None. M. Hurley: None. A. Shaibani: None. M. Gounis: None. M. Potts: None. B. Jahromi: None. A. Wakhloo: None. A. Puri: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Ansari, S., Kuhn, A., Honarmand, A., Hou, S., Khan, M., Chueh, J., Bom, I. v. d., Hurley, M., Shaibani, A., Gounis, M., Potts, M., Jahromi, B., Wakhloo, A., Puri, A. Tags: Oral abstracts Source Type: research

O-025 The Superiority of Thrombectomy over IV rtPA Monotherapy May be Associated with Thrombus Length - Results of the THERAPY Trial
ConclusionExtensive thrombus burden presents a challenge for stroke intervention, posing greater risk of complications and poor clinical outcome. However, this effect is dampened when IAT is the interventional modality, leading to a more favorable prognosis over IV-rtPA alone. This study finding supports the use of aspiration thrombectomy in treatment of extended thrombi, demonstrating relative advantages over thrombolytic monotherapy, and enables better clinical outcomes.DisclosuresR. von Kummer: 2; C; Penumbra, Inc. J. Mocco: 1; C; Penumbra, Inc. O. Zaidat: 6; C; Penumbra, Inc. P. Khatri: 1; C; Penumbra, Inc. R. Gupta: 6...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: von Kummer, R., Mocco, J., Zaidat, O., Khatri, P., Gupta, R., Frei, D., Lopes, D., Shownkeen, H., Berkhemer, O., Meyer, D., Chauke, M., Hak, S., Kuo, S., Buell, H., Bose, A., Sit, S., Yoo, A. Tags: Oral abstracts Source Type: research

P-001 Permanent Implantation of the Solitaire Device as a Bailout Technique for Large Vessel Intracranial Occlusions
ConclusionWith the recent over-whelming evidence demonstrating the effectiveness endovascular therapy in acute ischemic stroke, the expansion of stroke therapy requires that a variety of techniques be available to the operators. Permanent implantation of the Solitaire stent achieves adequate distal flow and good clinical outcomes in the setting of AIS. This case series suggests this technique provides a safe alternative for difficult cases refractory to other revascularization techniques.Key Wordsstroke, revascularization, stentDisclosuresJ. Houde: None. E. Barber: None. M. Kelly: 2; C; Medtronic. 4; C; Blockade. 6; C; Pen...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Houde, J., Barber, E., Kelly, M., Peeling, L. Tags: Oral poster abstracts Source Type: research

P-010 Association of Clot Burden Score with Radiographic and Clinical Outcomes Following Solitaire Stent Retriever Thrombectomy: Analysis of the SWIFT PRIME Trial
ConclusionsThe combination of IV thrombolysis and stent retriever thrombectomy with the Solitaire device is highly effective in achieving successful recanalization and a good clinical outcome throughout the entire range of CBS values.DisclosuresM. Mokin: None. E. Levy: 4; C; Intratech Medical Ltd., Blockade Medical LLC, Medina Medical. 6; C; Covidien (Medtronic), Abbott, Intratech Medical and Blockade Medical. A. Siddqui: 2; C; Codman & Shurtleff, Inc., Concentric Medical, ev3/Covidien Vascular Therapies, GuidePoint Global Consulting, Penumbra, Stryker, Pulsar Vascular, MicroVention, Lazarus Effect, Blockade Medical. 3...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Mokin, M., Levy, E., Siddqui, A., Goyal, M., Nogueira, R., Yavagal, D., Pereira, V., Saver, J. Tags: Oral poster abstracts Source Type: research

P-012 Longer Working Length of the Solitaire Retrieval Device Improves Revascularization
ConclusionsThe Solitaire 4 x 40 device showed a statistical trend for achieving better recanalization compared to the shorter devices. However due to our small sample size of patients undergoing treatment with the 4 x 40, further investigation is warranted to determine whether this result is maintained in larger sample size such as the STRATUS registry.DisclosuresW. Holloway: None. I. Akhtar: None. J. Halpin: None. C. Martin: None. N. Akhtar: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Holloway, W., Akhtar, I., Halpin, J., Martin, C., Akhtar, N. Tags: Oral poster abstracts Source Type: research

P-013 Use of the Solitaire Device for Emergency Revascularization of the Superior Mesenteric Artery
ConclusionsThe techniques and equipment used for acute stroke intervention may be suitable for acute recanalization of peripheral vessels, under the right circumstances. As with many surgical interventions, a multidisciplinary approach may at times yield a novel and effective strategy for a difficult clinical problem.DisclosuresJ. Dalfino: None. A. Paul: None. J. Hnath: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Dalfino, J., Paul, A., Hnath, J. Tags: Oral poster abstracts Source Type: research

P-021 Very Delayed Monocular Blindness Following Flow Diversion Treatment of Ophthalmic Artery Aneurysm
ConclusionMonocular vision loss remains a risk, even months to years following flow diversion of ICA aneurysms. Long term clinical follow-up is necessary to define the incidence of this complication.Abstract P-021 Figure 1DisclosuresT. Higashimori: None. D. Sandhu: None. J. Kim: None. A. Grande: None. M. Ezzeddine: None. R. Tummala: None. B. Jagadeesan: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Higashimori, T., Sandhu, D., Kim, J., Grande, A., Ezzeddine, M., Tummala, R., Jagadeesan, B. Tags: Oral poster abstracts Source Type: research

E-004 Factors Associated with Successful Revascularization using the Aspiration Component of ADAPT in the Treatment of Acute Ischemic Stroke
ConclusionsAspiration success was associated with younger age. There was a trend for aspiration failure to be associated with cardiogenic etiology and more difficult vascular anatomy. Our findings suggest that the ADAPT technique can be used for the vast majority of patients but it may be beneficial to use a SR primarily when performing thrombectomy in the elderly. Further research analyzing thrombus characteristics is needed.References1 Turk AS, Frei D, Fiorella D, et al. ADAPT FAST study: a direct aspiration first pass technique for acute stroke thrombectomy. J Neurointerv Surg 2014 ;6(4):260–4.2 Turk AS, Turner R,...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Mascitelli, J., Kellner, C., Oravec, C., DeLeacy, R., Oermann, E., Paramasivam, S., Fifi, J., Mocco, J. Tags: Electronic poster abstracts Source Type: research

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